Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FQT45_RS05815 Genome accession   NZ_LR595858
Coordinates   1194776..1195450 (-) Length   224 a.a.
NCBI ID   WP_077321968.1    Uniprot ID   A0A4U9XQR4
Organism   Streptococcus pseudoporcinus strain NCTC10228     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1189776..1200450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT45_RS05790 (NCTC10228_01196) - 1190034..1191311 (-) 1278 WP_077321978.1 pyrimidine-nucleoside phosphorylase -
  FQT45_RS05795 (NCTC10228_01197) - 1191308..1191898 (-) 591 WP_077321976.1 class I SAM-dependent methyltransferase -
  FQT45_RS05800 (NCTC10228_01198) coaA 1192165..1193085 (+) 921 WP_077321974.1 type I pantothenate kinase -
  FQT45_RS05805 (NCTC10228_01199) rpsT 1193145..1193387 (+) 243 WP_077321972.1 30S ribosomal protein S20 -
  FQT45_RS05810 (NCTC10228_01200) ciaH 1193464..1194783 (-) 1320 WP_077321970.1 sensor histidine kinase Regulator
  FQT45_RS05815 (NCTC10228_01201) ciaR 1194776..1195450 (-) 675 WP_077321968.1 response regulator transcription factor Regulator
  FQT45_RS05820 (NCTC10228_01202) - 1195802..1198351 (-) 2550 WP_077321967.1 M1 family metallopeptidase -
  FQT45_RS05825 (NCTC10228_01203) phoU 1198425..1199078 (-) 654 WP_007893157.1 phosphate signaling complex protein PhoU -
  FQT45_RS05830 (NCTC10228_01204) pstB 1199106..1199864 (-) 759 WP_077353821.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25638.44 Da        Isoelectric Point: 4.3545

>NTDB_id=1128489 FQT45_RS05815 WP_077321968.1 1194776..1195450(-) (ciaR) [Streptococcus pseudoporcinus strain NCTC10228]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFNENSITFGNLRVDLDRNAVKVNDSAVELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTDFATNLQTLRSVGYILKAYD

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1128489 FQT45_RS05815 WP_077321968.1 1194776..1195450(-) (ciaR) [Streptococcus pseudoporcinus strain NCTC10228]
ATGATAAAAATATTACTAGTTGAAGATGATTTAAGTTTATCGAATTCTATTTTTGACTTTCTCGATGATTTTGCTGATGT
TATGCAAGTTTTTGATGGAGATGAAGGTTTATATGAAGCAGAAAGTGGGGTTTATGATTTAATTCTTTTAGATTTAATGC
TCCCAGAAAAAAATGGCTTTCAAGTTCTAAAAGAGCTTAGAGAAAAGGATATTAAGACCCCTGTTTTAATTATGACTGCT
AAAGAAGGGTTAGATGATAAGGGACATGGTTTTGAATTAGGTGCTGATGACTATTTAACCAAGCCTTTTTACTTGGAAGA
ACTTAAAATGCGCATTCAAGCTCTTCTTAAGCGAACTGGTAAGTTTAACGAAAACAGTATTACGTTTGGTAATCTCAGAG
TTGACCTTGATCGGAATGCTGTGAAAGTGAATGATAGTGCCGTTGAACTATTAGGGAAAGAATATGATCTGCTCATCTAT
TTACTTCAAAATCAGAATGTTATTTTACCGAAATCCCAAATTTTTGATCGGATTTGGGGTTTTGATAGTGATACCACTAT
TTCGGTTGTAGAAGTTTATGTTTCTAAAATTCGAAAGAAATTAAAAGATACTGATTTTGCAACAAACTTACAGACCTTAC
GTAGCGTTGGCTACATTTTAAAAGCCTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9XQR4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.688

98.661

0.875
  ciaR Streptococcus pneumoniae Rx1

86.878

98.661

0.857
  ciaR Streptococcus pneumoniae D39

86.878

98.661

0.857
  ciaR Streptococcus pneumoniae TIGR4

86.878

98.661

0.857
  ciaR Streptococcus pneumoniae R6

86.878

98.661

0.857
  vicR Streptococcus mutans UA159

36.864

100

0.388
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379

Multiple sequence alignment