Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FQT45_RS05810 Genome accession   NZ_LR595858
Coordinates   1193464..1194783 (-) Length   439 a.a.
NCBI ID   WP_077321970.1    Uniprot ID   A0A4U9XN74
Organism   Streptococcus pseudoporcinus strain NCTC10228     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1188464..1199783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT45_RS05780 (NCTC10228_01194) - 1188986..1189375 (-) 390 WP_007893088.1 cytidine deaminase -
  FQT45_RS05785 (NCTC10228_01195) deoC 1189362..1190024 (-) 663 WP_077321980.1 deoxyribose-phosphate aldolase -
  FQT45_RS05790 (NCTC10228_01196) - 1190034..1191311 (-) 1278 WP_077321978.1 pyrimidine-nucleoside phosphorylase -
  FQT45_RS05795 (NCTC10228_01197) - 1191308..1191898 (-) 591 WP_077321976.1 class I SAM-dependent methyltransferase -
  FQT45_RS05800 (NCTC10228_01198) coaA 1192165..1193085 (+) 921 WP_077321974.1 type I pantothenate kinase -
  FQT45_RS05805 (NCTC10228_01199) rpsT 1193145..1193387 (+) 243 WP_077321972.1 30S ribosomal protein S20 -
  FQT45_RS05810 (NCTC10228_01200) ciaH 1193464..1194783 (-) 1320 WP_077321970.1 sensor histidine kinase Regulator
  FQT45_RS05815 (NCTC10228_01201) ciaR 1194776..1195450 (-) 675 WP_077321968.1 response regulator transcription factor Regulator
  FQT45_RS05820 (NCTC10228_01202) - 1195802..1198351 (-) 2550 WP_077321967.1 M1 family metallopeptidase -
  FQT45_RS05825 (NCTC10228_01203) phoU 1198425..1199078 (-) 654 WP_007893157.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50296.70 Da        Isoelectric Point: 9.0860

>NTDB_id=1128488 FQT45_RS05810 WP_077321970.1 1193464..1194783(-) (ciaH) [Streptococcus pseudoporcinus strain NCTC10228]
MTKYRALITSDNFDRFFHFFAVFTGIFVVMTVIILQIMKVGVYSSVDTSLTAVATHSTLYANRTMERISSFYFDGQDFNF
KTNLDDLKGKNSDQPVANTDIILFNANGMVINTFDALSNFQNFSFKKSDLNEIKTRKLVNYYGHEEKFHTITVRVHSNNY
PAVAYLMAVVNVEQSEKTNERYEKIIIIIMILFWLISILASIYLANWSNKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNESILDNSEAIASSLEEVRNMRILTTNLLNLARRDDGIKPEIVEISSHFFDGIFDNYKLIAEDYGKGFESVN
GVTKPIRMDKSLLKQLMTILFDNAIKYTDESGFIKITVRNTDKYFFITVEDNGPGIRDADKKKIFDRFYRVDKARTRSHG
GFGLGLSLAQQIVTSLKGTILVNDNKSKGSVFEVKLPLN

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1128488 FQT45_RS05810 WP_077321970.1 1193464..1194783(-) (ciaH) [Streptococcus pseudoporcinus strain NCTC10228]
ATGACTAAATATAGAGCTCTTATTACATCAGATAATTTTGACCGTTTCTTTCATTTCTTTGCCGTTTTTACAGGTATATT
TGTTGTTATGACGGTTATTATTTTGCAAATTATGAAAGTGGGCGTTTACTCATCAGTAGATACAAGCTTGACAGCTGTTG
CGACTCATTCAACCCTCTATGCTAATCGAACTATGGAAAGGATTTCCTCTTTCTATTTTGATGGTCAAGACTTCAATTTT
AAAACAAACCTAGATGATTTAAAAGGGAAAAATAGTGATCAACCCGTCGCAAATACTGATATTATTTTATTTAATGCTAA
TGGTATGGTGATTAATACCTTTGATGCGCTTTCTAATTTTCAAAATTTTTCTTTTAAAAAGAGTGATTTAAACGAAATCA
AAACCAGGAAATTGGTTAATTATTACGGTCATGAGGAAAAATTTCATACTATTACGGTTAGAGTTCATTCTAACAACTAC
CCAGCTGTTGCTTATTTAATGGCTGTTGTGAACGTAGAGCAATCTGAAAAAACGAATGAACGCTATGAAAAAATAATCAT
TATCATTATGATTCTATTTTGGCTTATTTCTATTTTGGCAAGTATCTATTTAGCCAATTGGAGTAACAAACCAATTCTCG
AAAGCTATGAAAAACAGAAGATGTTTGTTGAAAATGCCAGTCATGAATTAAGAACGCCTTTGGCTGTGCTCCAAAATCGT
TTAGAAACCCTTTTTCGCAAGCCCAACGAGAGTATTTTGGATAATAGCGAAGCAATTGCCTCAAGCTTGGAAGAGGTTCG
AAACATGAGAATATTAACAACTAATCTTCTGAACTTAGCTCGTCGGGATGATGGTATTAAACCTGAAATTGTAGAAATAT
CGAGTCACTTTTTTGATGGTATTTTTGATAATTATAAACTCATTGCTGAAGATTATGGAAAAGGTTTTGAGTCTGTTAAT
GGCGTTACTAAGCCAATTAGAATGGATAAGTCCCTTCTAAAACAATTAATGACAATTTTATTCGATAATGCAATTAAATA
TACAGATGAATCAGGTTTTATTAAAATCACTGTTAGAAACACAGATAAATATTTCTTTATTACTGTTGAAGATAATGGAC
CGGGGATTAGAGATGCTGATAAAAAGAAAATATTTGACCGTTTTTATCGAGTAGATAAAGCAAGAACAAGAAGTCATGGT
GGCTTTGGATTAGGTTTGTCACTGGCTCAACAAATCGTCACTTCCTTAAAGGGGACTATTCTTGTTAATGATAATAAAAG
CAAGGGGAGTGTCTTTGAGGTTAAACTTCCTCTAAATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-438)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9XN74

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.136

100

0.563
  ciaH Streptococcus pneumoniae Rx1

48.174

99.772

0.481
  ciaH Streptococcus pneumoniae D39

48.174

99.772

0.481
  ciaH Streptococcus pneumoniae R6

48.174

99.772

0.481
  ciaH Streptococcus pneumoniae TIGR4

48.174

99.772

0.481

Multiple sequence alignment