Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FQT67_RS05070 Genome accession   NZ_LR595857
Coordinates   988131..988805 (+) Length   224 a.a.
NCBI ID   WP_003060678.1    Uniprot ID   A0AAE9R380
Organism   Streptococcus sp. NCTC 11567 strain NCTC11567     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 983131..993805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT67_RS05055 (NCTC11567_01046) pstB 983700..984458 (+) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -
  FQT67_RS05060 (NCTC11567_01047) phoU 984536..985189 (+) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  FQT67_RS05065 (NCTC11567_01048) - 985390..987927 (+) 2538 WP_046177283.1 M1 family metallopeptidase -
  FQT67_RS05070 (NCTC11567_01049) ciaR 988131..988805 (+) 675 WP_003060678.1 response regulator transcription factor Regulator
  FQT67_RS05075 (NCTC11567_01050) ciaH 988798..990108 (+) 1311 WP_012766987.1 HAMP domain-containing sensor histidine kinase Regulator
  FQT67_RS05080 (NCTC11567_01051) rpsT 990266..990514 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  FQT67_RS05085 (NCTC11567_01052) coaA 990568..991488 (-) 921 WP_012766986.1 type I pantothenate kinase -
  FQT67_RS05090 (NCTC11567_01053) - 991757..992356 (+) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  FQT67_RS05095 (NCTC11567_01054) - 992343..993620 (+) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25601.58 Da        Isoelectric Point: 4.4684

>NTDB_id=1128429 FQT67_RS05070 WP_003060678.1 988131..988805(+) (ciaR) [Streptococcus sp. NCTC 11567 strain NCTC11567]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1128429 FQT67_RS05070 WP_003060678.1 988131..988805(+) (ciaR) [Streptococcus sp. NCTC 11567 strain NCTC11567]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGCTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375

Multiple sequence alignment