Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FQT67_RS05075 Genome accession   NZ_LR595857
Coordinates   988798..990108 (+) Length   436 a.a.
NCBI ID   WP_012766987.1    Uniprot ID   A0AB38Y432
Organism   Streptococcus sp. NCTC 11567 strain NCTC11567     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 983798..995108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT67_RS05060 (NCTC11567_01047) phoU 984536..985189 (+) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  FQT67_RS05065 (NCTC11567_01048) - 985390..987927 (+) 2538 WP_046177283.1 M1 family metallopeptidase -
  FQT67_RS05070 (NCTC11567_01049) ciaR 988131..988805 (+) 675 WP_003060678.1 response regulator transcription factor Regulator
  FQT67_RS05075 (NCTC11567_01050) ciaH 988798..990108 (+) 1311 WP_012766987.1 HAMP domain-containing sensor histidine kinase Regulator
  FQT67_RS05080 (NCTC11567_01051) rpsT 990266..990514 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  FQT67_RS05085 (NCTC11567_01052) coaA 990568..991488 (-) 921 WP_012766986.1 type I pantothenate kinase -
  FQT67_RS05090 (NCTC11567_01053) - 991757..992356 (+) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  FQT67_RS05095 (NCTC11567_01054) - 992343..993620 (+) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  FQT67_RS05100 (NCTC11567_01055) deoC 993636..994298 (+) 663 WP_046159693.1 deoxyribose-phosphate aldolase -
  FQT67_RS05105 (NCTC11567_01056) - 994285..994674 (+) 390 WP_003058840.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49917.46 Da        Isoelectric Point: 8.2375

>NTDB_id=1128430 FQT67_RS05075 WP_012766987.1 988798..990108(+) (ciaH) [Streptococcus sp. NCTC 11567 strain NCTC11567]
MNKLKKEVFSDQYNHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1128430 FQT67_RS05075 WP_012766987.1 988798..990108(+) (ciaH) [Streptococcus sp. NCTC 11567 strain NCTC11567]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACAACCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.37

100

0.516
  ciaH Streptococcus pneumoniae D39

51.37

100

0.516
  ciaH Streptococcus pneumoniae R6

51.37

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.37

100

0.516

Multiple sequence alignment