Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FGL17_RS04235 Genome accession   NZ_LR594052
Coordinates   846074..846748 (+) Length   224 a.a.
NCBI ID   WP_003085675.1    Uniprot ID   A0A4V0H320
Organism   Streptococcus porcinus strain NCTC10924     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 841074..851748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL17_RS04220 (NCTC10924_00848) pstB 841839..842597 (+) 759 WP_093958759.1 phosphate ABC transporter ATP-binding protein PstB -
  FGL17_RS04225 (NCTC10924_00849) phoU 842625..843278 (+) 654 WP_007893157.1 phosphate signaling complex protein PhoU -
  FGL17_RS04230 (NCTC10924_00850) - 843353..845902 (+) 2550 WP_093958758.1 M1 family metallopeptidase -
  FGL17_RS04235 (NCTC10924_00851) ciaR 846074..846748 (+) 675 WP_003085675.1 response regulator transcription factor Regulator
  FGL17_RS04240 (NCTC10924_00852) ciaH 846741..848060 (+) 1320 WP_003083461.1 sensor histidine kinase Regulator
  FGL17_RS04245 (NCTC10924_00853) rpsT 848135..848377 (-) 243 WP_081461234.1 30S ribosomal protein S20 -
  FGL17_RS04250 (NCTC10924_00854) coaA 848437..849357 (-) 921 WP_003083902.1 type I pantothenate kinase -
  FGL17_RS04255 (NCTC10924_00855) - 849623..850213 (+) 591 WP_003086066.1 class I SAM-dependent methyltransferase -
  FGL17_RS04260 (NCTC10924_00856) - 850210..851487 (+) 1278 WP_003084015.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25626.48 Da        Isoelectric Point: 4.4992

>NTDB_id=1128128 FGL17_RS04235 WP_003085675.1 846074..846748(+) (ciaR) [Streptococcus porcinus strain NCTC10924]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFNENSITFGNLRVDLNRNAVKVNDRAVELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKNTDFAANLQTLRSVGYILKAND

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1128128 FGL17_RS04235 WP_003085675.1 846074..846748(+) (ciaR) [Streptococcus porcinus strain NCTC10924]
ATGATAAAAATATTACTAGTTGAAGATGATTTAAGTTTATCAAATTCTATTTTTGACTTTCTCGATGATTTTGCGGACGT
TATGCAAGTTTTTGATGGAGATGAAGGTTTATATGAAGCAGAAAGTGGGGTTTATGATTTAATTCTTCTAGATTTAATGC
TTCCAGAAAAAAACGGTTTTCAAGTTTTAAAAGAGCTTAGAGAAAAAGATATTAAGACGCCTGTTTTAATTATGACAGCT
AAAGAAGGCTTAGATGATAAGGGACATGGTTTTGAACTAGGTGCTGATGACTATTTAACAAAACCCTTTTACTTGGAAGA
ACTTAAAATGCGTATTCAAGCCTTGCTTAAACGAACTGGCAAGTTTAACGAAAACAGTATTACATTTGGTAATCTCAGAG
TTGATCTTAATCGAAATGCTGTAAAAGTGAATGATAGGGCCGTTGAGCTATTAGGGAAAGAGTATGATTTGCTTATCTAT
TTACTTCAAAATCAGAATGTAATTTTACCAAAATCACAAATTTTTGATCGAATTTGGGGCTTTGATAGTGATACCACTAT
TTCGGTTGTGGAGGTCTATGTTTCTAAAATTCGAAAGAAATTAAAAAATACTGATTTTGCAGCAAACTTACAAACCTTAC
GTAGTGTTGGTTATATTTTAAAAGCAAATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H320

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.235

98.661

0.871
  ciaR Streptococcus pneumoniae Rx1

86.878

98.661

0.857
  ciaR Streptococcus pneumoniae D39

86.878

98.661

0.857
  ciaR Streptococcus pneumoniae R6

86.878

98.661

0.857
  ciaR Streptococcus pneumoniae TIGR4

86.878

98.661

0.857
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379
  vicR Streptococcus mutans UA159

35.593

100

0.375

Multiple sequence alignment