Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL17_RS04240 Genome accession   NZ_LR594052
Coordinates   846741..848060 (+) Length   439 a.a.
NCBI ID   WP_003083461.1    Uniprot ID   A0A4V0H660
Organism   Streptococcus porcinus strain NCTC10924     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 841741..853060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL17_RS04220 (NCTC10924_00848) pstB 841839..842597 (+) 759 WP_093958759.1 phosphate ABC transporter ATP-binding protein PstB -
  FGL17_RS04225 (NCTC10924_00849) phoU 842625..843278 (+) 654 WP_007893157.1 phosphate signaling complex protein PhoU -
  FGL17_RS04230 (NCTC10924_00850) - 843353..845902 (+) 2550 WP_093958758.1 M1 family metallopeptidase -
  FGL17_RS04235 (NCTC10924_00851) ciaR 846074..846748 (+) 675 WP_003085675.1 response regulator transcription factor Regulator
  FGL17_RS04240 (NCTC10924_00852) ciaH 846741..848060 (+) 1320 WP_003083461.1 sensor histidine kinase Regulator
  FGL17_RS04245 (NCTC10924_00853) rpsT 848135..848377 (-) 243 WP_081461234.1 30S ribosomal protein S20 -
  FGL17_RS04250 (NCTC10924_00854) coaA 848437..849357 (-) 921 WP_003083902.1 type I pantothenate kinase -
  FGL17_RS04255 (NCTC10924_00855) - 849623..850213 (+) 591 WP_003086066.1 class I SAM-dependent methyltransferase -
  FGL17_RS04260 (NCTC10924_00856) - 850210..851487 (+) 1278 WP_003084015.1 pyrimidine-nucleoside phosphorylase -
  FGL17_RS04265 (NCTC10924_00857) deoC 851497..852159 (+) 663 WP_093958757.1 deoxyribose-phosphate aldolase -
  FGL17_RS04270 (NCTC10924_00858) - 852146..852535 (+) 390 WP_003083268.1 cytidine deaminase -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50221.71 Da        Isoelectric Point: 9.0854

>NTDB_id=1128129 FGL17_RS04240 WP_003083461.1 846741..848060(+) (ciaH) [Streptococcus porcinus strain NCTC10924]
MTKYRAIITSDNFDRFFHFFAVFTGIFVVMTVIILQIMKVGVYSSVDTSLTAVATHSTLYANRTMERISSFYFDGQDLNF
KTNLDDLKGKNSDQPVANTDIILFNANGMVINTFDALSNFQNFSFKKSDLNEIKTRKLVNYYGHEEKFHTITVRVHSNNY
PSVAYLMAVVNVEQSEKTNERYEKIIIIIMILFWLISILASIYLANWSSKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNESILDNSEAIASSLEEVRNMRILTTNLLNLARRDDGIKPEIVEISSRFFDGIFDNYKLIAEEYGKGFESVN
TVTKPIRMDKSLLKQLMTILFDNAIKYTDESGFIKIIVRNTDKYLFITVEDNGPGITDADKKKIFDRFYRVDKARTRSHG
GFGLGLSLAQQIVTSLKGTILVNDNKGKGSVFEVKLPLN

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1128129 FGL17_RS04240 WP_003083461.1 846741..848060(+) (ciaH) [Streptococcus porcinus strain NCTC10924]
ATGACTAAATATAGAGCGATTATTACTTCGGATAACTTTGACCGTTTCTTTCATTTTTTTGCCGTTTTTACAGGTATATT
TGTGGTGATGACGGTTATTATTTTGCAAATCATGAAAGTAGGTGTCTACTCATCAGTAGATACAAGTTTGACAGCTGTTG
CGACTCACTCAACCCTATATGCTAACCGAACGATGGAAAGGATTTCCTCTTTCTATTTTGATGGACAAGATTTAAATTTC
AAAACAAATCTAGATGATTTAAAAGGGAAAAACAGTGATCAACCTGTCGCAAATACTGATATTATTCTATTTAATGCTAA
TGGTATGGTAATTAATACCTTTGATGCCCTTTCCAATTTTCAAAATTTCTCTTTTAAAAAGAGTGATTTAAACGAAATCA
AAACTCGAAAACTTGTTAATTACTACGGTCATGAGGAAAAGTTCCATACTATTACAGTTAGAGTGCATTCTAATAATTAC
CCATCTGTCGCCTATTTAATGGCTGTTGTTAATGTAGAGCAATCTGAAAAAACTAACGAACGCTATGAAAAAATAATTAT
TATAATCATGATCTTATTTTGGCTTATTTCTATTTTGGCAAGTATCTATTTAGCCAATTGGAGTAGCAAACCAATTCTTG
AAAGCTATGAAAAACAGAAGATGTTTGTTGAAAATGCCAGTCATGAATTAAGGACGCCTTTGGCCGTACTCCAAAATCGT
TTAGAAACTCTTTTTCGCAAACCCAACGAAAGTATCTTAGATAATAGCGAAGCAATTGCTTCAAGTTTAGAAGAGGTTCG
CAATATGAGAATCTTGACGACGAATCTTCTGAATTTAGCTCGTCGAGATGATGGCATTAAACCTGAAATAGTAGAGATAT
CAAGTCGTTTTTTTGATGGTATTTTTGATAATTATAAGCTAATTGCTGAAGAATATGGAAAAGGCTTTGAGTCTGTCAAT
ACCGTTACAAAGCCAATCAGAATGGACAAATCTCTATTAAAACAGTTAATGACAATTTTATTCGATAACGCGATTAAGTA
TACAGATGAGTCAGGTTTTATTAAAATCATTGTTAGAAATACGGATAAATATCTCTTTATTACTGTTGAAGATAATGGAC
CAGGTATTACAGATGCCGACAAAAAGAAAATTTTTGATCGTTTTTATCGAGTAGATAAAGCTAGAACAAGGAGTCATGGT
GGCTTTGGATTAGGGTTATCACTTGCTCAACAAATCGTCACTTCTTTAAAAGGAACTATTCTTGTTAATGATAATAAAGG
CAAGGGTAGTGTATTTGAGGTAAAACTTCCTCTAAATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H660

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.818

100

0.569
  ciaH Streptococcus pneumoniae Rx1

47.982

100

0.487
  ciaH Streptococcus pneumoniae D39

47.982

100

0.487
  ciaH Streptococcus pneumoniae R6

47.982

100

0.487
  ciaH Streptococcus pneumoniae TIGR4

47.982

100

0.487

Multiple sequence alignment