Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   FGL23_RS03805 Genome accession   NZ_LR594049
Coordinates   796303..797004 (+) Length   233 a.a.
NCBI ID   WP_008809004.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 791303..802004
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS03785 (NCTC10231_00755) - 791533..792846 (+) 1314 WP_061603698.1 glycosyltransferase family 4 protein -
  FGL23_RS10910 (NCTC10231_00756) - 792882..793049 (+) 168 WP_414162783.1 hypothetical protein -
  FGL23_RS03795 (NCTC10231_00758) - 793513..794139 (+) 627 WP_081106375.1 AAA family ATPase -
  FGL23_RS03800 (NCTC10231_00759) thrS 794150..796093 (+) 1944 WP_061603699.1 threonine--tRNA ligase -
  FGL23_RS03805 (NCTC10231_00760) micA 796303..797004 (+) 702 WP_008809004.1 response regulator YycF Regulator
  FGL23_RS03810 (NCTC10231_00761) micB 796997..798358 (+) 1362 WP_060970310.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL23_RS03815 (NCTC10231_00762) vicX 798351..799154 (+) 804 WP_045634630.1 MBL fold metallo-hydrolase Regulator
  FGL23_RS03820 (NCTC10231_00763) - 799189..799545 (+) 357 WP_045773784.1 YbaN family protein -
  FGL23_RS03825 (NCTC10231_00764) rnc 799788..800486 (+) 699 WP_061603700.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26790.54 Da        Isoelectric Point: 4.6297

>NTDB_id=1127963 FGL23_RS03805 WP_008809004.1 796303..797004(+) (micA) [Streptococcus gordonii strain NCTC10231]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQESEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1127963 FGL23_RS03805 WP_008809004.1 796303..797004(+) (micA) [Streptococcus gordonii strain NCTC10231]
ATGAAGAAAATATTAGTTGTAGATGACGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGCCGTGAAGCTCTTGAGATGTTTGAAGCAGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAACGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGTCTCGAGATTGGAGCAGACGACTATGTGACCAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAGTGAAAAGGGTTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCAGATGCTTTTGTTGCTAAGAAACATGGTGAGGAACTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCCAGTCATGTTGGTCAAGTAATGACACGCGAACACCTACTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGCCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTACTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

79.574

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373

Multiple sequence alignment