Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FGL05_RS08940 Genome accession   NZ_LR594044
Coordinates   1778455..1779705 (-) Length   416 a.a.
NCBI ID   WP_020917669.1    Uniprot ID   A0AB33APT2
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1773455..1784705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS08915 (NCTC8796_01870) - 1773628..1773819 (-) 192 WP_020915953.1 DUF951 domain-containing protein -
  FGL05_RS08920 - 1773830..1774620 (-) 791 Protein_1719 diacylglycerol kinase family protein -
  FGL05_RS08925 (NCTC8796_01874) dnaN 1774751..1775887 (-) 1137 WP_020915952.1 DNA polymerase III subunit beta -
  FGL05_RS08930 (NCTC8796_01875) dnaA 1776046..1777401 (-) 1356 WP_020915951.1 chromosomal replication initiator protein DnaA -
  FGL05_RS08935 (NCTC8796_01876) spo0J 1777605..1778387 (-) 783 WP_020917670.1 ParB/RepB/Spo0J family partition protein Regulator
  FGL05_RS08940 (NCTC8796_01877) htrA 1778455..1779705 (-) 1251 WP_020917669.1 trypsin-like peptidase domain-containing protein Regulator
  FGL05_RS08945 (NCTC8796_01878) rlmH 1779920..1780399 (+) 480 WP_020917668.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FGL05_RS08965 - 1781237..1782575 (-) 1339 Protein_1725 IS3 family transposase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 43306.51 Da        Isoelectric Point: 4.7284

>NTDB_id=1127708 FGL05_RS08940 WP_020917669.1 1778455..1779705(-) (htrA) [Streptococcus lutetiensis strain NCTC8796]
MKKITFQKVNYKKILKPLSVILVGFIGGVAGTLLILNMAGISINNVSGSSTKTTTSKVSYSNTNDTTKAVEKVREAVVSV
INYQSNSSSNDLYMQMFGGNLDNNTNNGSDSDLSIASEGSGVIYKKDGNSAYVVTNNHVVDGASQIEIMLSDGTKVVGEL
VGTDTYSDIAVVKIASDKVTTVAEFANSDKITVGETAIAIGSPLGTDYANSVTQGIVSSLSRTVTMTNDDGETISTNAIQ
TDAAINPGNSGGALINIEGQVIGINSSKISSTSDSGSGNSVEGMGFAIPANDVVKIINQLEANGKVIRPALGITMANLSD
LSTTTISRLNIPTSVTSGIVVASVQSGMPAEGVLKKYDVITAIDDKDVSSITDLQSVLYGHSTGDSIKVTFYRGTDKKTE
TIKLTKTTQDLSSSNQ

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=1127708 FGL05_RS08940 WP_020917669.1 1778455..1779705(-) (htrA) [Streptococcus lutetiensis strain NCTC8796]
GTGAAAAAAATAACATTTCAAAAAGTCAATTACAAAAAAATCCTTAAACCACTATCCGTTATTTTAGTTGGTTTCATCGG
AGGAGTTGCTGGGACCTTACTCATTTTGAATATGGCTGGCATCTCAATCAATAATGTTAGTGGTTCAAGTACAAAAACTA
CAACAAGTAAAGTAAGTTACTCAAATACTAATGATACGACAAAAGCTGTCGAAAAAGTGAGAGAAGCAGTCGTATCAGTC
ATCAATTATCAATCAAATAGCTCTTCAAATGATTTGTATATGCAAATGTTTGGTGGCAATTTAGACAATAACACTAATAA
TGGATCAGATAGTGATTTAAGTATCGCTAGTGAAGGTTCTGGGGTTATTTACAAAAAAGACGGCAATTCTGCTTATGTCG
TTACTAATAACCACGTTGTCGATGGTGCTAGTCAAATCGAAATCATGCTTTCTGACGGTACAAAAGTAGTCGGTGAATTA
GTCGGTACCGATACATACTCAGATATCGCCGTTGTCAAAATTGCTTCTGATAAAGTCACAACGGTAGCTGAATTTGCTAA
TTCAGATAAAATTACTGTTGGTGAAACAGCCATTGCTATTGGTAGCCCTCTAGGTACTGATTATGCTAACTCTGTGACAC
AAGGAATTGTCTCAAGTCTAAGCCGTACAGTTACAATGACTAACGACGATGGCGAAACAATTTCAACCAATGCTATCCAA
ACTGATGCCGCTATTAACCCAGGTAACTCTGGTGGTGCTTTGATTAACATTGAAGGACAAGTAATCGGTATTAATTCAAG
TAAAATCTCTTCTACCTCAGATTCTGGATCAGGTAATTCTGTAGAAGGTATGGGATTTGCTATTCCAGCTAATGATGTGG
TTAAAATTATTAATCAATTAGAAGCAAACGGAAAAGTTATTCGTCCAGCACTTGGTATCACAATGGCTAACCTAAGCGAT
TTATCAACAACAACAATCAGTCGCCTAAATATTCCAACTAGCGTCACATCTGGTATCGTCGTTGCTTCAGTTCAATCAGG
TATGCCTGCTGAAGGAGTACTTAAAAAATACGATGTAATCACAGCTATTGATGATAAAGATGTCTCTTCTATCACAGATC
TTCAAAGTGTTCTTTACGGTCATTCAACTGGAGATTCTATTAAAGTAACCTTCTATCGTGGTACTGACAAGAAAACAGAA
ACTATTAAACTAACGAAAACAACACAAGACCTCTCTTCATCAAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(119-264)

Peptidase family M50 (Peptidase_M50)

(59-410)

PDZ domain (PDZ_2)

(309-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.838

96.394

0.625
  htrA Streptococcus gordonii str. Challis substr. CH1

60.741

97.356

0.591
  htrA Streptococcus mitis NCTC 12261

58.596

99.279

0.582
  htrA Streptococcus pneumoniae TIGR4

58.968

97.837

0.577
  htrA Streptococcus pneumoniae D39

58.968

97.837

0.577
  htrA Streptococcus pneumoniae Rx1

58.968

97.837

0.577
  htrA Streptococcus pneumoniae R6

58.968

97.837

0.577

Multiple sequence alignment