Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FGL05_RS08580 Genome accession   NZ_LR594044
Coordinates   1725171..1726079 (-) Length   302 a.a.
NCBI ID   WP_111712550.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1720171..1731079
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS08555 (NCTC8796_01800) - 1720409..1722202 (-) 1794 WP_111712551.1 acyltransferase family protein -
  FGL05_RS08560 (NCTC8796_01801) - 1722199..1722579 (-) 381 WP_006531314.1 membrane protein -
  FGL05_RS08565 (NCTC8796_01802) - 1722597..1723028 (-) 432 WP_014334179.1 low molecular weight protein-tyrosine-phosphatase -
  FGL05_RS09170 (NCTC8796_01804) - 1723592..1723798 (-) 207 WP_197712753.1 hypothetical protein -
  FGL05_RS08575 (NCTC8796_01805) ruvB 1723971..1724969 (-) 999 WP_020916203.1 Holliday junction branch migration DNA helicase RuvB -
  FGL05_RS08580 (NCTC8796_01806) comR 1725171..1726079 (-) 909 WP_111712550.1 XRE family transcriptional regulator Regulator
  FGL05_RS08585 (NCTC8796_01807) purB 1726236..1727534 (-) 1299 WP_058813549.1 adenylosuccinate lyase -
  FGL05_RS09550 - 1727624..1727719 (-) 96 Protein_1688 phosphoribosylaminoimidazole carboxylase -
  FGL05_RS08595 (NCTC8796_01808) purK 1727722..1728813 (-) 1092 WP_111698145.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  FGL05_RS08600 (NCTC8796_01809) purE 1728800..1729288 (-) 489 WP_058813548.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  FGL05_RS08605 (NCTC8796_01810) - 1729288..1729737 (-) 450 WP_111712549.1 DUF523 domain-containing protein -
  FGL05_RS08610 (NCTC8796_01811) purD 1729727..1730989 (-) 1263 WP_111712548.1 phosphoribosylamine--glycine ligase -

Sequence

Protein


Download         Length: 302 a.a.        Molecular weight: 35761.85 Da        Isoelectric Point: 4.7213

>NTDB_id=1127706 FGL05_RS08580 WP_111712550.1 1725171..1726079(-) (comR) [Streptococcus lutetiensis strain NCTC8796]
MEKFGEKIRLMREEKEISREEFYGDETELSVRQLARIELNQSIPNLSKASFIANRLGVKLGTLTDGDSLELPKRYKELKY
LLLRTPTYGDQVRLDRKNDYFDEIAEVFYDVIPEEERLIIDCLQSKFDVHFSEDVNFGEGILNDYFGQVNRKKVFTINDL
ILIDLYFACLSSAKKFEGIYSLNFYDDLMKRLVNQKHVSPETDLILNNVLLNNIDLAFQFKREYYIERVITISEKIMTEI
HDFQRRPILSLVEWKYYLKFKHDFALAEQSFTNATLFARLVGDTYLENKLKEEWQLDIDAVE

Nucleotide


Download         Length: 909 bp        

>NTDB_id=1127706 FGL05_RS08580 WP_111712550.1 1725171..1726079(-) (comR) [Streptococcus lutetiensis strain NCTC8796]
GTGGAAAAATTTGGGGAGAAGATCCGCTTGATGCGGGAGGAAAAGGAAATCTCACGTGAAGAATTCTATGGGGATGAAAC
AGAATTATCGGTAAGACAATTAGCTAGAATTGAGTTGAACCAATCAATACCCAATCTCAGTAAAGCAAGCTTTATTGCCA
ATCGTCTGGGAGTGAAATTAGGTACCTTAACTGATGGTGACAGTTTAGAATTACCTAAGCGGTATAAAGAGTTGAAGTAT
TTACTTCTTCGAACACCTACATATGGAGACCAGGTACGACTTGATCGAAAAAATGACTATTTTGATGAGATTGCTGAAGT
ATTTTATGATGTTATTCCAGAAGAAGAACGGTTAATCATTGATTGTTTACAATCAAAATTCGATGTTCATTTTAGTGAAG
ATGTCAATTTTGGAGAGGGTATTTTAAATGATTATTTTGGTCAAGTTAATCGAAAGAAAGTTTTTACCATTAATGATTTA
ATTTTGATTGATCTTTACTTTGCTTGTCTTTCTTCTGCTAAGAAGTTTGAAGGAATTTATAGTTTGAATTTTTACGATGA
TTTGATGAAAAGGTTGGTAAATCAAAAGCATGTTTCACCTGAGACTGATTTAATTTTAAATAATGTATTGTTAAATAATA
TTGACTTAGCATTCCAATTTAAACGAGAATATTATATTGAGCGTGTTATTACAATCAGTGAAAAAATTATGACAGAGATT
CATGATTTTCAACGTCGTCCGATTTTAAGTTTGGTGGAGTGGAAGTATTATCTGAAATTTAAACATGACTTTGCTTTAGC
AGAACAGTCATTTACGAATGCAACATTATTTGCACGATTGGTTGGTGATACTTATTTAGAAAATAAACTTAAAGAAGAAT
GGCAACTTGATATTGATGCTGTGGAGTAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-61)

ComR tetratricopeptide (ComR_TPR)

(72-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

98.973

96.689

0.957
  comR Streptococcus mutans UA159

52.349

98.675

0.517
  comR Streptococcus pyogenes MGAS8232

50.662

100

0.507
  comR Streptococcus pyogenes MGAS315

45.364

100

0.454
  comR Streptococcus suis D9

36.424

100

0.364
  comR Streptococcus suis P1/7

36.7

98.344

0.361
  comR Streptococcus suis 05ZYH33

36.7

98.344

0.361

Multiple sequence alignment