Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FGL05_RS02485 Genome accession   NZ_LR594044
Coordinates   493064..493774 (+) Length   236 a.a.
NCBI ID   WP_039696509.1    Uniprot ID   A0A6G8HYC0
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 488064..498774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS02455 (NCTC8796_00527) - 488623..488925 (+) 303 WP_020917228.1 hypothetical protein -
  FGL05_RS02460 (NCTC8796_00528) - 489137..489745 (+) 609 WP_111712944.1 VTT domain-containing protein -
  FGL05_RS02465 (NCTC8796_00529) - 489782..490429 (-) 648 WP_111712943.1 amino acid ABC transporter permease -
  FGL05_RS02470 (NCTC8796_00530) - 490442..491149 (-) 708 WP_020917225.1 amino acid ABC transporter permease -
  FGL05_RS02475 (NCTC8796_00531) - 491165..491977 (-) 813 WP_020917224.1 transporter substrate-binding domain-containing protein -
  FGL05_RS02480 (NCTC8796_00532) - 491994..492752 (-) 759 WP_020917223.1 amino acid ABC transporter ATP-binding protein -
  FGL05_RS02485 (NCTC8796_00533) vicR 493064..493774 (+) 711 WP_039696509.1 response regulator YycF Regulator
  FGL05_RS02490 (NCTC8796_00534) vicK 493767..495119 (+) 1353 WP_111712942.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL05_RS02495 (NCTC8796_00535) vicX 495120..495929 (+) 810 WP_058814132.1 MBL fold metallo-hydrolase Regulator
  FGL05_RS02500 (NCTC8796_00536) rnc 496150..496836 (+) 687 WP_020917219.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27121.90 Da        Isoelectric Point: 4.7040

>NTDB_id=1127665 FGL05_RS02485 WP_039696509.1 493064..493774(+) (vicR) [Streptococcus lutetiensis strain NCTC8796]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIAKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1127665 FGL05_RS02485 WP_039696509.1 493064..493774(+) (vicR) [Streptococcus lutetiensis strain NCTC8796]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTATGA
AACTGTTACGGCTTTTGATGGTCGTGAAGCTATTGCTAAATTTGAAGAAGAAAATCCTGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGATGGACTTGAAGTTGCAAAAGAAGTTCGTAAAACAAGTCATATTCCGATTATTATGCTTTCTGCT
AAAGATAGCGAATTCGATAAAGTTATCGGTCTTGAAATCGGTGCAGATGACTATGTTACAAAACCTTTCTCAAATCGTGA
ATTGTTAGCACGTGTCAAAGCACACCTTCGTCGTACTGAGAACATCGAATCAGCCGTCGCTGAGGAAAATGCTTCTTCAT
CAAATTCTGAAATTACCATCGGCGATTTGAAGATTTTGCCTGATGCCTTTGTTGCTCAAAAACGTGGTGAAGACATCGAA
TTAACACACCGTGAATTTGAATTACTTCATCACTTAGCTACTCACATGGGACAAGTGATGACGCGTGAATACCTTCTGGA
AACTGTTTGGGGTTATGATTACTTTGGTGATGTCCGCACAGTTGACGTTACCATTCGTCGTTTGCGTGAAAAAATCGAAG
ACACTCCGAGTCGTCCAGAATACATTTTGACACGTCGCGGTGTTGGATACTACATGAAGTCTTATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HYC0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.205

99.153

0.775
  covR Streptococcus salivarius strain HSISS4

46.983

98.305

0.462
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

98.305

0.449
  scnR Streptococcus mutans UA159

36.441

100

0.364

Multiple sequence alignment