Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FGL05_RS02490 Genome accession   NZ_LR594044
Coordinates   493767..495119 (+) Length   450 a.a.
NCBI ID   WP_111712942.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC8796     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 488767..500119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL05_RS02460 (NCTC8796_00528) - 489137..489745 (+) 609 WP_111712944.1 VTT domain-containing protein -
  FGL05_RS02465 (NCTC8796_00529) - 489782..490429 (-) 648 WP_111712943.1 amino acid ABC transporter permease -
  FGL05_RS02470 (NCTC8796_00530) - 490442..491149 (-) 708 WP_020917225.1 amino acid ABC transporter permease -
  FGL05_RS02475 (NCTC8796_00531) - 491165..491977 (-) 813 WP_020917224.1 transporter substrate-binding domain-containing protein -
  FGL05_RS02480 (NCTC8796_00532) - 491994..492752 (-) 759 WP_020917223.1 amino acid ABC transporter ATP-binding protein -
  FGL05_RS02485 (NCTC8796_00533) vicR 493064..493774 (+) 711 WP_039696509.1 response regulator YycF Regulator
  FGL05_RS02490 (NCTC8796_00534) vicK 493767..495119 (+) 1353 WP_111712942.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL05_RS02495 (NCTC8796_00535) vicX 495120..495929 (+) 810 WP_058814132.1 MBL fold metallo-hydrolase Regulator
  FGL05_RS02500 (NCTC8796_00536) rnc 496150..496836 (+) 687 WP_020917219.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51377.36 Da        Isoelectric Point: 4.7779

>NTDB_id=1127666 FGL05_RS02490 WP_111712942.1 493767..495119(+) (vicK) [Streptococcus lutetiensis strain NCTC8796]
MNDTMVQNQYLFEQAILFLLAFVAIYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDNED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1127666 FGL05_RS02490 WP_111712942.1 493767..495119(+) (vicK) [Streptococcus lutetiensis strain NCTC8796]
ATGAATGATACAATGGTACAGAATCAATATCTGTTTGAACAAGCCATTCTCTTCTTGCTAGCTTTTGTAGCCATTTATTT
TATTCATTTGGCTATCAGAGACTATAGAACGTCTGTTAATATTCGTCGATTAAGTGGTAAGGTTCGTGAACTGATTACAG
GAAAATACACAGAAGATATTATCATTGAAAAAGACAGAGATTTAGCAGAGTTAGCTGGTCAGTTAAATGATTTGTCAACT
GTCTTTCGTTTAGCTCAAGAAAATCTAGCCCAAGAAAAGAATCGTTTGGCAAGTATTTTGTCTTACATGACTGATGGGGT
GCTAGCGACTGACCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAGCGTGAAGAAG
CTCTTGGGATGAATATCGTTGACATTCTTGGTGATGATAGCGATTATTCTTACCATGATTTGGTGTCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGTGATGAGACGGGAGAATTTATCACTTTGCGTATTCGATTTGCCTTGAATCGTAGAGATAGTGG
ATTTATTTCTGGTCTGATTGCCGTCTTGCACGATACAACGGAACAAGAAAAAGAAGACCGCGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCATGAGTTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAAGCACTGGATGAAGGGGCTTTGAAA
GAAGATATTGCACCAAGTTTCATCAAAGTTTCTTTGGATGAAACCAATCGTATGATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTCGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACTAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAAAGTCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCAATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACACAAGTCTTGGATAATATCCTAAACAATGCCATTAAGTACTCACCAGA
CGGTGGTAAAATCACTGTTAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATAACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

64.237

97.556

0.627

Multiple sequence alignment