Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FGL06_RS06825 Genome accession   NZ_LR594042
Coordinates   1375417..1376127 (-) Length   236 a.a.
NCBI ID   WP_021142846.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370417..1381127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS06810 (NCTC8133_01380) rnc 1372365..1373051 (-) 687 WP_021142842.1 ribonuclease III -
  FGL06_RS06815 (NCTC8133_01381) vicX 1373262..1374071 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  FGL06_RS06820 (NCTC8133_01382) vicK 1374072..1375424 (-) 1353 WP_045797686.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL06_RS06825 (NCTC8133_01383) vicR 1375417..1376127 (-) 711 WP_021142846.1 response regulator YycF Regulator
  FGL06_RS06830 (NCTC8133_01384) - 1376435..1377199 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  FGL06_RS06835 (NCTC8133_01385) - 1377204..1378013 (+) 810 WP_126438024.1 transporter substrate-binding domain-containing protein -
  FGL06_RS06840 (NCTC8133_01386) - 1378029..1378733 (+) 705 WP_039698014.1 amino acid ABC transporter permease -
  FGL06_RS06845 (NCTC8133_01387) - 1378743..1379390 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  FGL06_RS06850 (NCTC8133_01388) - 1379422..1380030 (-) 609 WP_021142851.1 TVP38/TMEM64 family protein -
  FGL06_RS06855 (NCTC8133_01389) - 1380248..1380544 (-) 297 WP_126438025.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27179.94 Da        Isoelectric Point: 4.6553

>NTDB_id=1127586 FGL06_RS06825 WP_021142846.1 1375417..1376127(-) (vicR) [Streptococcus equinus strain NCTC8133]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIEKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1127586 FGL06_RS06825 WP_021142846.1 1375417..1376127(-) (vicR) [Streptococcus equinus strain NCTC8133]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTACGA
AACAGTTACGGCTTTTGATGGTCGTGAAGCTATTGAAAAATTTGAAGAAGAAAATCCTGATTTGATTATTTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTCGCAAAAGAAGTTCGTAAAACAAGTCATATTCCTATTATTATGCTATCAGCA
AAAGATAGTGAATTTGATAAAGTTATCGGTCTTGAAATCGGTGCTGACGACTACGTGACAAAACCATTTTCAAACCGCGA
ATTGTTGGCTCGTGTCAAGGCACACCTTCGCCGCACTGAAAATATCGAATCTGCAGTTGCTGAAGAAAATGCGTCTTCTT
CAAACTCAGAAATCACAATCGGTGACTTGAAAATCTTGCCTGATGCATTTGTGGCACAAAAACGTGGTGAAGACATTGAA
TTAACACACCGTGAGTTTGAATTGTTGCACCATTTGGCAACTCACATGGGACAAGTAATGACACGTGAATACCTTTTGGA
AACTGTCTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGACGTAACAATCCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGTCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGATATTACATGAAGTCTTATGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.632

99.153

0.78
  covR Streptococcus salivarius strain HSISS4

47.414

98.305

0.466
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

36.864

100

0.369

Multiple sequence alignment