Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FGL06_RS06820 Genome accession   NZ_LR594042
Coordinates   1374072..1375424 (-) Length   450 a.a.
NCBI ID   WP_045797686.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1369072..1380424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS06810 (NCTC8133_01380) rnc 1372365..1373051 (-) 687 WP_021142842.1 ribonuclease III -
  FGL06_RS06815 (NCTC8133_01381) vicX 1373262..1374071 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  FGL06_RS06820 (NCTC8133_01382) vicK 1374072..1375424 (-) 1353 WP_045797686.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL06_RS06825 (NCTC8133_01383) vicR 1375417..1376127 (-) 711 WP_021142846.1 response regulator YycF Regulator
  FGL06_RS06830 (NCTC8133_01384) - 1376435..1377199 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  FGL06_RS06835 (NCTC8133_01385) - 1377204..1378013 (+) 810 WP_126438024.1 transporter substrate-binding domain-containing protein -
  FGL06_RS06840 (NCTC8133_01386) - 1378029..1378733 (+) 705 WP_039698014.1 amino acid ABC transporter permease -
  FGL06_RS06845 (NCTC8133_01387) - 1378743..1379390 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  FGL06_RS06850 (NCTC8133_01388) - 1379422..1380030 (-) 609 WP_021142851.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51364.32 Da        Isoelectric Point: 4.7300

>NTDB_id=1127585 FGL06_RS06820 WP_045797686.1 1374072..1375424(-) (vicK) [Streptococcus equinus strain NCTC8133]
MNSIMSQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYTYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1127585 FGL06_RS06820 WP_045797686.1 1374072..1375424(-) (vicK) [Streptococcus equinus strain NCTC8133]
ATGAATAGTATAATGTCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGCTTGGCTCAGGAAAATCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTACATGACTGACGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAGACAGCTCAGCAGCAACTTAATCTGGAACGCGAAGAAG
CTCTTGGAATGAATATTGTTGATATTCTTGGGGACGATAGCGATTATACCTACCATGATTTGGTTTCTAAGACACCTGAG
ATTGTTCTAAATCGCCGTGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTAAATCGTCGTGATAGTGG
CTTTATCTCAGGGTTGATTGCTGTTTTACATGATACAACGGAACAAGAAAAAGAAGACCGAGAACGTCGTTTATTCGTAT
CAAATGTTAGTCACGAATTGCGTACACCGTTGACATCTGTGAAATCATATTTGGAAGCTTTGGATGAAGGTGCCCTTAAA
GAAGATATTGCACCAAGTTTTATTAAAGTTTCTCTTGATGAAACAAACCGCATGATTCGAATGATTTCTGATTTGCTCAA
TCTGTCTCGAATTGATAATCAAACTGTTCAGCTTGAAGTTGAAATGACTAATTTTACAGCATTTATGACATCAATTTTGA
ACCGTTTTGACCAAATTAAGAGTCAACACACTGTCGCTGGTAAGCAGTACGAGATTGTCAGAGATTATCCAATCAAGTCT
ATCTGGTTAGAAATTGACCCAGATAAAATGACTCAAGTTCTGGATAATATCCTTAATAATGCGATTAAGTATTCGCCAGA
TGGTGGTAAAATCACTGTCAGCATGAAGACGACTGAGACACAGTTGATTATTTCAATTTCTGATGAGGGTCTTGGTATTC
CTAAGAAAGATTTGCCGCTAATCTTTGACCGATTCTATCGTGTTGACAAGGCTAGAAGTCGTGCTCAAGGTGGTTCAGGA
CTTGGTCTTGCGATTGCAAAAGAAATTGTTAAACAACACAAAGGATTTATTTGGGCTCAAAGTACTTATGGAAAAGGCTC
AACCTTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGACGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622

Multiple sequence alignment