Detailed information NTG1127543

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FGL06_RS00285
• Genome accession: NZ_LR594042
• Coordinates: 45161..46072 (+)
• Length: 303 a.a.
• NCBI ID: WP_039691866.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC8133
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 40161..51072

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL06_RS00260 (NCTC8133_00051)	-	41361..41810 (+)	450	WP_126437520.1	DUF523 domain-containing protein	-
FGL06_RS00265 (NCTC8133_00052)	purE	41810..42298 (+)	489	WP_021141395.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
FGL06_RS00270 (NCTC8133_00053)	purK	42285..43376 (+)	1092	WP_126437521.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FGL06_RS00275 (NCTC8133_00054)	-	43398..43622 (+)	225	WP_027968247.1	hypothetical protein	-
FGL06_RS00280 (NCTC8133_00055)	purB	43713..45011 (+)	1299	WP_024344772.1	adenylosuccinate lyase	-
FGL06_RS00285 (NCTC8133_00056)	comR	45161..46072 (+)	912	WP_039691866.1	helix-turn-helix domain-containing protein	Regulator
FGL06_RS00290 (NCTC8133_00057)	ruvB	46243..47241 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
FGL06_RS00295 (NCTC8133_00058)	-	47451..47882 (+)	432	WP_126437522.1	low molecular weight protein-tyrosine-phosphatase	-
FGL06_RS00300 (NCTC8133_00059)	-	47899..48279 (+)	381	WP_021141401.1	MORN repeat-containing protein	-
FGL06_RS00305 (NCTC8133_00060)	-	48276..50069 (+)	1794	WP_126437523.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35514.77 Da
• Isoelectric Point: 4.7033

>NTDB_id=1127543 FGL06_RS00285 WP_039691866.1 45161..46072(+) (comR) [Streptococcus equinus strain NCTC8133]
MEVKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKEL
KYLILRTPTYKDEKRVNLRDSYFDEIYSDFYDDLPEEEQLIVECMRSKADVFLTDNSNLATKLLEDYFYQTKSKSHYSIN
DLIIIDLYMVCANASNYEYFMFDKDEFIGIAKNLLEQENHFSLAEIFVLNNILFGSLSLLVDLKMWDEVELTLDVLKGIM
AKIQDFHKKPVLNMIEWKYILERFGQTEKAQKLYEEAVLYANLIGDAYLANKITEEWIKDTTT

Nucleotide

• Length: 912 bp

>NTDB_id=1127543 FGL06_RS00285 WP_039691866.1 45161..46072(+) (comR) [Streptococcus equinus strain NCTC8133]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGA
CGAGACCGAATTATCTGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCCCAATTCA
TTGCTAATCGCCTTGGCGTAAAACTTGGAACCCTGACAGACGGCGATAGCTTAGAATTACCAAAGCGGTATAAAGAGCTG
AAGTATTTAATTTTGCGTACACCAACGTATAAAGATGAAAAGCGTGTGAATTTAAGAGATTCTTATTTTGATGAGATTTA
CTCTGACTTTTACGATGACCTTCCTGAGGAGGAGCAATTAATCGTGGAGTGCATGCGCTCAAAAGCAGATGTCTTTTTAA
CTGATAATAGTAATTTAGCCACAAAGTTGTTAGAAGACTATTTTTATCAAACAAAATCAAAATCGCATTATTCGATTAAT
GATTTAATCATAATTGATTTATATATGGTTTGTGCAAATGCTTCAAATTATGAATATTTTATGTTTGATAAAGATGAATT
TATTGGTATAGCTAAGAATCTATTAGAACAAGAAAATCACTTTTCGCTAGCAGAAATTTTTGTCTTAAATAATATTTTAT
TTGGTAGTTTGAGCTTGTTGGTTGATTTAAAAATGTGGGACGAAGTGGAATTGACTTTAGATGTTTTAAAAGGAATTATG
GCTAAAATTCAAGATTTTCATAAGAAGCCAGTTTTGAATATGATTGAGTGGAAGTATATTTTGGAACGTTTTGGTCAAAC
AGAAAAGGCTCAAAAATTATATGAAGAGGCAGTGTTATATGCAAATTTGATAGGTGATGCTTATTTAGCTAATAAAATAA
CAGAAGAATGGATAAAAGATACAACAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (74-297)

• Helix-turn-helix (HTH_3) (10-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.632	94.059	0.495
comR	Streptococcus pyogenes MGAS8232	46.844	99.34	0.465
comR	Streptococcus mutans UA159	46.823	98.68	0.462
comR	Streptococcus pyogenes MGAS315	46.309	98.35	0.455
comR	Streptococcus suis P1/7	39.731	98.02	0.389
comR	Streptococcus suis 05ZYH33	39.731	98.02	0.389
comR	Streptococcus suis D9	37.419	100	0.383