Detailed information NTG1127499

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: FGL12_RS08030
• Genome accession: NZ_LR594041
• Coordinates: 1661180..1662133 (-)
• Length: 317 a.a.
• NCBI ID: WP_012130640.1
• Uniprot ID: A8AYJ3
• Organism: Streptococcus gordonii strain NCTC9124
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1656180..1667133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL12_RS08010 (NCTC9124_01612)	-	1656684..1657169 (-)	486	WP_012130636.1	LURP-one-related family protein	-
FGL12_RS08015 (NCTC9124_01614)	prsA	1657398..1658327 (-)	930	WP_012130637.1	peptidylprolyl isomerase PrsA	-
FGL12_RS08020 (NCTC9124_01615)	-	1658530..1659216 (-)	687	WP_012130638.1	O-methyltransferase	-
FGL12_RS08025 (NCTC9124_01616)	pepF	1659218..1661020 (-)	1803	WP_012130639.1	oligoendopeptidase F	Regulator
FGL12_RS08030 (NCTC9124_01617)	coiA	1661180..1662133 (-)	954	WP_012130640.1	competence protein CoiA family protein	Machinery gene
FGL12_RS08035 (NCTC9124_01618)	celB	1662226..1663581 (-)	1356	WP_012130641.1	PTS cellobiose transporter subunit IIC	-
FGL12_RS08040 (NCTC9124_01619)	-	1663602..1664087 (-)	486	WP_012130642.1	hypothetical protein	-
FGL12_RS08045 (NCTC9124_01620)	-	1664115..1664432 (-)	318	WP_012130643.1	PTS cellobiose transporter subunit IIA	-
FGL12_RS08050 (NCTC9124_01621)	-	1664449..1666440 (-)	1992	WP_041789748.1	BglG family transcription antiterminator	-
FGL12_RS08055 (NCTC9124_01622)	-	1666489..1666803 (-)	315	WP_012130645.1	PTS cellobiose transporter subunit IIB	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38047.71 Da
• Isoelectric Point: 8.9808

>NTDB_id=1127499 FGL12_RS08030 WP_012130640.1 1661180..1662133(-) (coiA) [Streptococcus gordonii strain NCTC9124]
MFSARDKNGKILHLLKESSLSKGDYFCPECGGPVRLKKGKIMQPHFAHIRLSDCHYSVENESKEHLNLKAALFRWANQTT
RVDVEVFLPDLQQVADVLVDERLALEVQCSSLSQDRLWERSQRYRQAGYQVLWLLGKKLWLRQTLTPLQKQFLYFSQNMG
FHIWELDEERKMLRLKYLIHEDLHGQLQYKEKEFPFEKGKLLDILRLPFSKQEMSSFFVKSDPDICHYIRQQLYYRNPKW
MKIQASYYQKEKNLLTMSREEFYPQVRPIRSDQPLCQISQDLSAYYENFQRYYHHSPDKKYQIVYPPAFYASLDQSC

Nucleotide

• Length: 954 bp

>NTDB_id=1127499 FGL12_RS08030 WP_012130640.1 1661180..1662133(-) (coiA) [Streptococcus gordonii strain NCTC9124]
ATGTTTTCAGCGCGTGATAAGAATGGGAAGATCCTTCATTTACTAAAGGAGTCATCCCTTTCAAAAGGAGATTATTTTTG
CCCAGAGTGTGGAGGGCCTGTCCGTTTGAAAAAGGGGAAAATCATGCAGCCCCATTTCGCGCATATTCGTTTATCCGACT
GTCATTATAGTGTTGAAAATGAAAGCAAAGAGCATCTGAACCTTAAGGCCGCCCTTTTTCGCTGGGCCAATCAAACGACA
AGAGTAGATGTCGAAGTGTTTTTGCCAGACTTGCAGCAGGTAGCGGATGTCTTAGTTGATGAGCGTCTTGCTTTAGAAGT
TCAGTGTAGCAGTCTTTCCCAAGATAGACTTTGGGAGCGGAGCCAAAGATATCGCCAAGCTGGCTATCAAGTCCTCTGGC
TCCTGGGAAAGAAACTCTGGCTCAGGCAAACTTTGACACCCTTGCAGAAGCAATTCCTATATTTCAGTCAAAACATGGGT
TTTCATATCTGGGAATTGGACGAGGAAAGAAAGATGCTAAGGCTGAAGTATTTGATTCATGAAGACCTTCATGGACAACT
CCAGTATAAAGAAAAAGAATTTCCTTTTGAAAAAGGAAAATTATTAGATATCTTACGATTGCCTTTTAGCAAGCAGGAAA
TGAGTAGTTTCTTCGTGAAGTCAGATCCTGATATTTGCCATTATATCCGACAGCAACTCTATTATCGAAATCCCAAGTGG
ATGAAAATACAGGCCAGCTATTATCAAAAAGAAAAAAATCTTTTAACCATGTCCAGAGAAGAATTTTATCCGCAAGTGCG
CCCGATTCGTTCAGACCAGCCTTTATGCCAGATTTCCCAAGACCTATCTGCTTATTATGAAAACTTTCAGCGCTATTATC
ATCATTCTCCAGATAAAAAGTACCAGATCGTCTACCCACCAGCCTTTTACGCAAGTTTAGATCAGTCTTGCTGA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-258)

3D structure

• AlphaFold DB: A8AYJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	56.774	97.792	0.555
coiA	Streptococcus pneumoniae TIGR4	54.516	97.792	0.533
coiA	Streptococcus pneumoniae Rx1	54.516	97.792	0.533
coiA	Streptococcus pneumoniae D39	54.516	97.792	0.533
coiA	Streptococcus pneumoniae R6	54.516	97.792	0.533
coiA	Lactococcus lactis subsp. cremoris KW2	42.813	100	0.442