Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   FGL12_RS06135 Genome accession   NZ_LR594041
Coordinates   1278219..1279061 (-) Length   280 a.a.
NCBI ID   WP_012000600.1    Uniprot ID   A8AXH5
Organism   Streptococcus gordonii strain NCTC9124     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1273219..1284061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS06115 (NCTC9124_01228) - 1274044..1274538 (-) 495 WP_012000596.1 phosphoribosylanthranilate isomerase -
  FGL12_RS06120 (NCTC9124_01229) - 1274558..1275265 (-) 708 WP_012000597.1 DUF3307 domain-containing protein -
  FGL12_RS06125 (NCTC9124_01230) - 1275249..1275932 (-) 684 WP_012000598.1 SatD family protein -
  FGL12_RS06130 (NCTC9124_01231) topA 1276042..1278135 (-) 2094 WP_012000599.1 type I DNA topoisomerase -
  FGL12_RS06135 (NCTC9124_01232) dprA/cilB/dalA 1278219..1279061 (-) 843 WP_012000600.1 DNA-processing protein DprA Machinery gene
  FGL12_RS06140 (NCTC9124_01233) - 1279188..1279766 (-) 579 WP_012000601.1 sugar O-acetyltransferase -
  FGL12_RS06145 (NCTC9124_01234) - 1279763..1280581 (-) 819 WP_012000602.1 PRD domain-containing protein -
  FGL12_RS06150 (NCTC9124_01235) - 1280599..1281363 (-) 765 WP_012000603.1 ribonuclease HII -
  FGL12_RS06155 (NCTC9124_01236) ylqF 1281350..1282201 (-) 852 WP_012000604.1 ribosome biogenesis GTPase YlqF -
  FGL12_RS06160 (NCTC9124_01237) - 1282346..1282684 (-) 339 WP_008808609.1 ATP cone domain-containing protein -
  FGL12_RS06165 (NCTC9124_01238) dapA 1282925..1283860 (-) 936 WP_012000606.1 4-hydroxy-tetrahydrodipicolinate synthase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31321.07 Da        Isoelectric Point: 6.2444

>NTDB_id=1127495 FGL12_RS06135 WP_012000600.1 1278219..1279061(-) (dprA/cilB/dalA) [Streptococcus gordonii strain NCTC9124]
MKNYDIYKMKHAGLTNGQVLNVLRYVENKEKELSLRDIAVVSECRNPALFMERYKQIDDDFLKKSFEEFPSFSILDEIYP
WDLSEIYNPPVLLFYQGNIDLLELPKVAVVGSRDSSKLGNQSVQKIIKELNNELIIVSGLARGIDTAAHMAALQNGGRTI
AVIGTGLDVFYPKANKKLQSYIGKNHLVLSEYGPGEQPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGKSDGCHHLIQEGAKCIMSGSDVLFEFDF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1127495 FGL12_RS06135 WP_012000600.1 1278219..1279061(-) (dprA/cilB/dalA) [Streptococcus gordonii strain NCTC9124]
ATGAAAAACTATGATATTTATAAAATGAAGCATGCTGGACTGACTAATGGACAAGTTCTTAATGTCTTGAGATATGTTGA
AAACAAGGAAAAGGAGCTTTCTTTGCGTGATATAGCGGTGGTTTCAGAGTGCCGTAATCCTGCCCTGTTTATGGAACGCT
ATAAGCAAATTGACGACGATTTCTTAAAGAAATCCTTTGAGGAATTTCCCTCTTTTTCTATCTTGGATGAAATTTATCCC
TGGGACTTGAGTGAGATATATAACCCACCTGTTCTTTTGTTTTATCAGGGAAATATTGATCTACTTGAATTGCCAAAAGT
AGCAGTAGTCGGAAGTCGTGATAGTAGTAAGCTTGGAAACCAGTCCGTTCAGAAAATTATTAAAGAATTGAATAATGAAT
TAATCATTGTGAGTGGATTAGCGCGTGGGATTGACACAGCTGCTCATATGGCAGCTTTACAGAATGGTGGAAGAACTATA
GCTGTTATTGGAACTGGATTAGATGTTTTTTATCCTAAAGCCAATAAAAAACTTCAGTCATATATTGGCAAAAATCATCT
GGTTTTATCAGAATACGGTCCCGGCGAACAGCCTTTGAAGTTTCATTTTCCTGAACGTAATCGAATTATCGCAGGTTTGT
GCAGAGGCGTCATTGTTGCTGAAGCTAAGATGAGATCTGGAAGCTTGATAACTTGTGAGCGAGCGATGGAAGAAGGAAGA
GATGTATTTGCTATTCCTGGATCTATTCTTGATGGAAAGTCTGATGGTTGTCATCATCTGATTCAAGAAGGCGCTAAGTG
CATTATGTCAGGCTCTGATGTTCTATTTGAGTTTGATTTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AXH5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

78.929

100

0.789
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

78.571

100

0.786
  dprA/cilB/dalA Streptococcus pneumoniae D39

78.571

100

0.786
  dprA/cilB/dalA Streptococcus pneumoniae R6

78.571

100

0.786
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

78.571

100

0.786
  dprA/cilB/dalA Streptococcus mitis SK321

78.214

100

0.782
  dprA Streptococcus mutans UA159

66.429

100

0.664
  dprA Lactococcus lactis subsp. cremoris KW2

57.914

99.286

0.575
  dprA Legionella pneumophila strain ERS1305867

43.75

85.714

0.375

Multiple sequence alignment