Detailed information NTG1127380

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: FGK96_RS10420
• Genome accession: NZ_LR594036
• Coordinates: 2158481..2159683 (+)
• Length: 400 a.a.
• NCBI ID: WP_138083463.1
• Uniprot ID: A0A4V0A3G9
• Organism: Streptococcus porcinus strain NCTC10710
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2153481..2164683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK96_RS10395 (NCTC10710_02146)	-	2154696..2157284 (+)	2589	WP_138083462.1	YfhO family protein	-
FGK96_RS10415 (NCTC10710_02150)	rlmH	2157805..2158284 (-)	480	WP_138083538.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
FGK96_RS10420 (NCTC10710_02151)	htrA	2158481..2159683 (+)	1203	WP_138083463.1	S1C family serine protease	Regulator
FGK96_RS10425 (NCTC10710_02152)	spo0J	2159760..2160533 (+)	774	WP_138083464.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 42616.46 Da
• Isoelectric Point: 7.3097

>NTDB_id=1127380 FGK96_RS10420 WP_138083463.1 2158481..2159683(+) (htrA) [Streptococcus porcinus strain NCTC10710]
MTIIKNIWKLVGILVVGILGGIIAFFTLSVFHPDFTNNQEGITKPTTISKVTYKNTTNTTKAVKVVQNAVVSVINYRKSS
PANQANDIFGEPKSSLNDDNGYSIYSEGSGVIYKKEGKDAYIVTNNHVIDKTDRIEILLADGSKIVGKLVGADTYSDLAV
VKVPSEKIKSVAKFANSANLNVGEVAIAIGSPLGTEYANSVTEGIVSSLSRTVTLKNDEGQTISTNAIQTDAAINPGNSG
GALINIEGQVIGINSSKISQSNASGNAVEGIGFAIPANDVIKIINQLEAKGEVIRPAIGIRMVNLGDLSTNALNQLQVPE
NVKGGIVVASVIDNMPAVGKLKQYDIITEIDGETVNTKSDLQTILYSHEINDSIKVTYYRGKDKKTTTIKLTKTTKDLNE

Nucleotide

• Length: 1203 bp

>NTDB_id=1127380 FGK96_RS10420 WP_138083463.1 2158481..2159683(+) (htrA) [Streptococcus porcinus strain NCTC10710]
GTGACAATAATAAAAAATATTTGGAAACTAGTTGGTATCTTGGTTGTTGGTATTCTTGGTGGTATAATCGCTTTTTTCAC
ATTAAGTGTCTTTCACCCTGATTTTACTAATAATCAAGAAGGAATTACTAAGCCTACAACAATTAGTAAAGTAACTTATA
AAAATACAACCAATACTACAAAAGCTGTTAAGGTTGTTCAAAATGCTGTCGTTTCGGTCATTAATTATCGAAAATCTAGT
CCTGCTAATCAAGCAAATGATATCTTTGGTGAACCTAAATCCTCTTTAAATGACGATAATGGTTACTCTATCTACAGCGA
AGGGTCAGGAGTCATTTACAAAAAAGAAGGTAAGGATGCCTATATTGTAACGAATAACCATGTTATTGACAAAACAGATA
GAATTGAAATCTTATTAGCTGATGGTTCAAAAATAGTTGGTAAACTAGTAGGAGCGGACACCTATTCTGACTTAGCAGTT
GTTAAAGTTCCTTCTGAAAAAATAAAATCAGTTGCTAAATTTGCTAACTCTGCCAATTTAAACGTTGGGGAAGTAGCTAT
TGCTATTGGTAGTCCCCTTGGAACTGAATATGCTAACTCTGTCACTGAAGGAATAGTCTCAAGCTTAAGTAGAACAGTAA
CACTTAAAAATGATGAGGGTCAGACAATTTCAACAAATGCTATTCAAACAGATGCTGCTATTAATCCAGGAAATTCTGGA
GGTGCTTTAATTAATATTGAAGGACAAGTTATTGGTATTAATTCAAGCAAAATCTCACAATCTAATGCTTCTGGCAATGC
AGTTGAAGGAATAGGATTTGCAATTCCAGCTAATGATGTCATTAAAATTATTAATCAGCTGGAAGCTAAGGGTGAAGTTA
TTCGACCAGCTATCGGAATTAGAATGGTTAACCTTGGTGACTTATCGACAAATGCCTTGAACCAACTTCAAGTACCAGAA
AATGTTAAAGGTGGTATTGTAGTTGCTTCCGTGATAGACAATATGCCTGCTGTTGGTAAATTGAAACAATATGACATAAT
CACTGAAATCGATGGTGAAACAGTAAATACAAAATCTGATTTACAAACTATACTTTATAGTCATGAGATAAATGATAGCA
TTAAAGTTACTTACTATCGCGGTAAAGATAAGAAAACAACTACTATCAAATTGACCAAAACAACAAAAGATTTAAATGAA
TAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

• PDZ domain (PDZ_2) (296-391)

3D structure

• AlphaFold DB: A0A4V0A3G9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.847	97.75	0.585
htrA	Streptococcus gordonii str. Challis substr. CH1	53.383	99.75	0.532
htrA	Streptococcus pneumoniae Rx1	52.897	99.25	0.525
htrA	Streptococcus pneumoniae R6	52.897	99.25	0.525
htrA	Streptococcus pneumoniae TIGR4	52.897	99.25	0.525
htrA	Streptococcus pneumoniae D39	52.897	99.25	0.525
htrA	Streptococcus mitis NCTC 12261	52.897	99.25	0.525