Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FGK96_RS04005 Genome accession   NZ_LR594036
Coordinates   825885..826559 (+) Length   224 a.a.
NCBI ID   WP_138081628.1    Uniprot ID   -
Organism   Streptococcus porcinus strain NCTC10710     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 820885..831559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK96_RS03990 (NCTC10710_00819) pstB 821650..822408 (+) 759 WP_138081624.1 phosphate ABC transporter ATP-binding protein PstB -
  FGK96_RS03995 (NCTC10710_00820) phoU 822436..823089 (+) 654 WP_007893157.1 phosphate signaling complex protein PhoU -
  FGK96_RS04000 (NCTC10710_00821) - 823164..825713 (+) 2550 WP_138081626.1 M1 family metallopeptidase -
  FGK96_RS04005 (NCTC10710_00822) ciaR 825885..826559 (+) 675 WP_138081628.1 response regulator transcription factor Regulator
  FGK96_RS04010 (NCTC10710_00823) ciaH 826552..827871 (+) 1320 WP_138081630.1 sensor histidine kinase Regulator
  FGK96_RS04015 (NCTC10710_00824) rpsT 828149..828391 (-) 243 WP_081461234.1 30S ribosomal protein S20 -
  FGK96_RS04020 (NCTC10710_00825) coaA 828451..829371 (-) 921 WP_138081632.1 type I pantothenate kinase -
  FGK96_RS04025 (NCTC10710_00826) - 829638..830228 (+) 591 WP_138081634.1 class I SAM-dependent methyltransferase -
  FGK96_RS04030 (NCTC10710_00827) - 830225..831502 (+) 1278 WP_138081636.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25624.41 Da        Isoelectric Point: 4.3545

>NTDB_id=1127341 FGK96_RS04005 WP_138081628.1 825885..826559(+) (ciaR) [Streptococcus porcinus strain NCTC10710]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFNEYSITFGNLRVDLDRNSVKVNDSAVELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTDFAANLQTLRSVGYILKAND

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1127341 FGK96_RS04005 WP_138081628.1 825885..826559(+) (ciaR) [Streptococcus porcinus strain NCTC10710]
ATGATAAAAATATTACTAGTTGAAGATGATTTAAGTTTATCAAATTCTATTTTTGACTTTCTCGATGATTTTGCTGATGT
TATGCAAGTTTTTGATGGAGATGAAGGTTTATATGAAGCAGAAAGCGGGGTTTATGATTTAATTCTTTTAGATCTAATGC
TCCCAGAAAAAAATGGTTTTCAAGTTCTAAAAGAGCTTAGAGAAAAGGATATCAAGACCCCTGTTTTAATTATGACTGCC
AAAGAAGGTTTGGATGATAAGGGGCATGGTTTTGAACTAGGAGCTGATGACTATTTAACAAAACCTTTTTACTTGGAAGA
GCTTAAAATGCGTATTCAAGCCTTACTTAAACGAACCGGCAAGTTTAATGAATACAGTATTACATTTGGTAATCTTAGAG
TTGACCTTGATCGTAATTCTGTGAAAGTGAATGATAGTGCCGTTGAACTATTAGGGAAAGAATATGATTTACTCATCTAT
TTGCTTCAAAATCAGAATGTTATTTTACCAAAATCACAAATTTTTGATCGGATTTGGGGCTTTGACAGTGATACCACTAT
TTCGGTTGTAGAAGTCTATGTTTCTAAAATTCGAAAGAAATTAAAAGATACTGATTTTGCAGCAAACTTACAGACCTTAC
GTAGTGTTGGCTACATTTTAAAAGCAAATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.235

98.661

0.871
  ciaR Streptococcus pneumoniae Rx1

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae D39

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae R6

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae TIGR4

86.425

98.661

0.853
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379
  vicR Streptococcus mutans UA159

35.593

100

0.375

Multiple sequence alignment