Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FGL04_RS03265 Genome accession   NZ_LR594035
Coordinates   589858..590568 (+) Length   236 a.a.
NCBI ID   WP_138068210.1    Uniprot ID   A0A4U9XV80
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 584858..595568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS03240 (NCTC5385_00689) - 585265..586284 (+) 1020 WP_138068206.1 DUF3114 domain-containing protein -
  FGL04_RS03245 (NCTC5385_00690) - 586604..587251 (-) 648 WP_077323106.1 amino acid ABC transporter permease -
  FGL04_RS03250 (NCTC5385_00691) - 587267..587971 (-) 705 WP_138068207.1 amino acid ABC transporter permease -
  FGL04_RS03255 (NCTC5385_00692) - 587989..588807 (-) 819 WP_138068208.1 transporter substrate-binding domain-containing protein -
  FGL04_RS03260 (NCTC5385_00693) - 588820..589599 (-) 780 WP_138068209.1 amino acid ABC transporter ATP-binding protein -
  FGL04_RS03265 (NCTC5385_00694) vicR 589858..590568 (+) 711 WP_138068210.1 response regulator YycF Regulator
  FGL04_RS03270 (NCTC5385_00695) vicK 590561..591919 (+) 1359 WP_007893475.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL04_RS03275 (NCTC5385_00696) vicX 591920..592732 (+) 813 WP_138068211.1 MBL fold metallo-hydrolase Regulator
  FGL04_RS03280 (NCTC5385_00697) rnc 592838..593530 (+) 693 WP_138068212.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27041.97 Da        Isoelectric Point: 5.1038

>NTDB_id=1127290 FGL04_RS03265 WP_138068210.1 589858..590568(+) (vicR) [Streptococcus pseudoporcinus strain NCTC5385]
MKKILIVDDEKPISDIIKFNLTKEGYDIMTAFDGREAIAAFEEAKPDLVILDLMLPEMDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEDNASSGNQELTIGNLQILPDAFLAKKYGKEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKQHD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1127290 FGL04_RS03265 WP_138068210.1 589858..590568(+) (vicR) [Streptococcus pseudoporcinus strain NCTC5385]
ATGAAAAAAATCCTCATTGTAGACGATGAAAAACCTATTTCAGACATTATAAAGTTTAATTTGACCAAAGAAGGTTATGA
TATCATGACAGCTTTTGATGGTCGAGAAGCCATCGCAGCCTTTGAAGAAGCTAAACCTGATTTGGTTATTTTGGATTTGA
TGTTACCAGAAATGGATGGTCTTGAAGTTGCAAAAGAAATTCGAAAAACCAGTCATATCCCTATAATTATGCTTTCTGCC
AAAGATAGTGAATTTGATAAGGTCATTGGTTTAGAGATTGGTGCGGACGACTATGTAACAAAACCTTTTTCAAATCGTGA
GCTCCTAGCGCGTGTTAAAGCCCATTTGCGACGCACCGAAACGATTGAAACAGCTGTTGCTGAAGATAATGCTTCCTCAG
GAAACCAAGAATTAACTATCGGTAATCTCCAGATTCTGCCAGATGCTTTCTTGGCTAAAAAATATGGTAAGGAAGTTGAA
TTGACACATCGCGAATTTGAATTATTACACCATTTAGCTAATCATATCGGGCAAGTCATGACTCGTGAACATTTATTAGA
AACGGTCTGGGGCTATGATTATTTTGGTGATGTGAGAACTGTTGATGTTACCGTACGACGTTTGAGAGAAAAAATTGAAG
ATACACCAAGCCGTCCTGAATATATTTTGACAAGACGTGGCGTTGGCTATTATATGAAACAGCATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9XV80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.288

100

0.873
  micA Streptococcus pneumoniae Cp1015

77.447

99.576

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.348

98.729

0.428
  covR Streptococcus salivarius strain HSISS4

42.735

99.153

0.424
  scnR Streptococcus mutans UA159

37.768

98.729

0.373

Multiple sequence alignment