Detailed information
Bioinformatically predicted
Overview
| Name | vicK | Type | Regulator |
| Locus tag | FGL04_RS03270 | Genome accession | NZ_LR594035 |
| Coordinates | 590561..591919 (+) | Length | 452 a.a. |
| NCBI ID | WP_007893475.1 | Uniprot ID | - |
| Organism | Streptococcus pseudoporcinus strain NCTC5385 | ||
| Function | repress comCDE expression; repress comX expression (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 591920..640672 | 590561..591919 | flank | 1 |
Gene organization within MGE regions
Location: 590561..640672
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGL04_RS03270 (NCTC5385_00695) | vicK | 590561..591919 (+) | 1359 | WP_007893475.1 | cell wall metabolism sensor histidine kinase VicK | Regulator |
| FGL04_RS03275 (NCTC5385_00696) | vicX | 591920..592732 (+) | 813 | WP_138068211.1 | MBL fold metallo-hydrolase | Regulator |
| FGL04_RS03280 (NCTC5385_00697) | rnc | 592838..593530 (+) | 693 | WP_138068212.1 | ribonuclease III | - |
| FGL04_RS03285 (NCTC5385_00698) | smc | 593531..597076 (+) | 3546 | WP_138068213.1 | chromosome segregation protein SMC | - |
| FGL04_RS03295 (NCTC5385_00701) | - | 598905..599126 (+) | 222 | WP_138068214.1 | helix-turn-helix domain-containing protein | - |
| FGL04_RS03300 (NCTC5385_00702) | - | 599130..599477 (+) | 348 | WP_225247763.1 | VRR-NUC domain-containing protein | - |
| FGL04_RS03310 (NCTC5385_00705) | - | 600753..602393 (+) | 1641 | WP_225247764.1 | HsdM family class I SAM-dependent methyltransferase | - |
| FGL04_RS03315 (NCTC5385_00706) | - | 602402..603487 (+) | 1086 | WP_138068216.1 | restriction endonuclease subunit S | - |
| FGL04_RS03325 (NCTC5385_00709) | - | 604783..605169 (+) | 387 | WP_138068218.1 | hypothetical protein | - |
| FGL04_RS03330 (NCTC5385_00711) | - | 605371..606476 (+) | 1106 | WP_138068165.1 | IS3 family transposase | - |
| FGL04_RS03335 (NCTC5385_00712) | - | 606524..607336 (+) | 813 | WP_138069148.1 | Cof-type HAD-IIB family hydrolase | - |
| FGL04_RS03340 (NCTC5385_00713) | - | 607326..608150 (+) | 825 | WP_138068219.1 | Cof-type HAD-IIB family hydrolase | - |
| FGL04_RS03345 (NCTC5385_00714) | ftsY | 608150..609634 (+) | 1485 | WP_138068220.1 | signal recognition particle-docking protein FtsY | - |
| FGL04_RS03350 (NCTC5385_00715) | - | 609660..610159 (+) | 500 | Protein_631 | YkgJ family cysteine cluster protein | - |
| FGL04_RS03355 (NCTC5385_00716) | - | 610696..611376 (+) | 681 | WP_225247765.1 | hypothetical protein | - |
| FGL04_RS03360 (NCTC5385_00718) | - | 611429..612534 (+) | 1106 | WP_138068165.1 | IS3 family transposase | - |
| FGL04_RS10915 (NCTC5385_00719) | - | 612527..613066 (+) | 540 | WP_225247766.1 | hypothetical protein | - |
| FGL04_RS03370 (NCTC5385_00720) | - | 613014..613622 (+) | 609 | WP_138068221.1 | SDR family oxidoreductase | - |
| FGL04_RS03375 (NCTC5385_00721) | - | 613704..615068 (-) | 1365 | WP_138068222.1 | MFS transporter | - |
| FGL04_RS03380 (NCTC5385_00722) | - | 615181..615996 (-) | 816 | WP_138068223.1 | TIGR03943 family putative permease subunit | - |
| FGL04_RS03385 (NCTC5385_00723) | - | 615993..616901 (-) | 909 | WP_138068224.1 | permease | - |
| FGL04_RS10700 (NCTC5385_00724) | - | 616950..617111 (-) | 162 | WP_171011228.1 | SPJ_0845 family protein | - |
| FGL04_RS11250 | - | 617353..617481 (+) | 129 | WP_269902559.1 | hypothetical protein | - |
| FGL04_RS03390 (NCTC5385_00725) | - | 617540..617761 (+) | 222 | WP_416236967.1 | cupin domain-containing protein | - |
| FGL04_RS03395 (NCTC5385_00727) | - | 617814..618919 (+) | 1106 | WP_138068165.1 | IS3 family transposase | - |
| FGL04_RS03400 (NCTC5385_00728) | - | 618962..619243 (+) | 282 | WP_225247846.1 | cupin domain-containing protein | - |
| FGL04_RS03405 (NCTC5385_00729) | - | 619323..620051 (+) | 729 | WP_138068225.1 | response regulator transcription factor | - |
| FGL04_RS03410 (NCTC5385_00730) | pnpS | 620035..621369 (+) | 1335 | WP_138068226.1 | two-component system histidine kinase PnpS | - |
| FGL04_RS03415 (NCTC5385_00731) | - | 621528..622406 (+) | 879 | WP_138068227.1 | substrate-binding domain-containing protein | - |
| FGL04_RS03420 (NCTC5385_00732) | pstC | 622470..623333 (+) | 864 | WP_138068228.1 | phosphate ABC transporter permease subunit PstC | - |
| FGL04_RS03425 (NCTC5385_00733) | pstA | 623326..624141 (+) | 816 | WP_138068229.1 | phosphate ABC transporter permease PstA | - |
| FGL04_RS03430 (NCTC5385_00734) | pstB | 624144..624896 (+) | 753 | WP_138068230.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| FGL04_RS03435 (NCTC5385_00735) | phoU | 624911..625564 (+) | 654 | WP_138068231.1 | phosphate signaling complex protein PhoU | - |
| FGL04_RS03440 (NCTC5385_00736) | - | 626211..627346 (-) | 1136 | Protein_651 | IS3 family transposase | - |
| FGL04_RS03445 (NCTC5385_00738) | - | 627468..629600 (+) | 2133 | WP_171011229.1 | Tex family protein | - |
| FGL04_RS03450 (NCTC5385_00739) | - | 629587..630030 (+) | 444 | WP_171011230.1 | SprT family protein | - |
| FGL04_RS03455 (NCTC5385_00740) | - | 630090..630365 (+) | 276 | WP_007892892.1 | PspC domain-containing protein | - |
| FGL04_RS03460 (NCTC5385_00741) | hprK | 630560..631489 (+) | 930 | WP_138068234.1 | HPr(Ser) kinase/phosphatase | - |
| FGL04_RS03465 (NCTC5385_00742) | lgt | 631491..632270 (+) | 780 | WP_138068235.1 | prolipoprotein diacylglyceryl transferase | - |
| FGL04_RS03470 (NCTC5385_00743) | - | 632288..632692 (+) | 405 | WP_007892823.1 | DUF948 domain-containing protein | - |
| FGL04_RS03475 (NCTC5385_00744) | - | 632689..633246 (+) | 558 | WP_138068236.1 | YtxH domain-containing protein | - |
| FGL04_RS03480 (NCTC5385_00745) | - | 633463..633747 (-) | 285 | WP_138068237.1 | DUF3270 domain-containing protein | - |
| FGL04_RS03485 (NCTC5385_00746) | - | 633902..634828 (+) | 927 | WP_138068238.1 | peptidase U32 family protein | - |
| FGL04_RS03490 (NCTC5385_00747) | - | 634936..636222 (+) | 1287 | WP_171011269.1 | peptidase U32 family protein | - |
| FGL04_RS03495 (NCTC5385_00748) | - | 636282..636593 (-) | 312 | WP_138068240.1 | hypothetical protein | - |
| FGL04_RS03500 (NCTC5385_00749) | - | 636709..636924 (+) | 216 | WP_007892833.1 | YdbC family protein | - |
| FGL04_RS03505 (NCTC5385_00751) | - | 637066..638171 (+) | 1106 | WP_138068165.1 | IS3 family transposase | - |
| FGL04_RS11255 (NCTC5385_00752) | - | 638443..638577 (-) | 135 | WP_007892832.1 | hypothetical protein | - |
| FGL04_RS03510 (NCTC5385_00753) | - | 638639..639538 (-) | 900 | Protein_666 | NAD(P)/FAD-dependent oxidoreductase | - |
Sequence
Protein
Download Length: 452 a.a. Molecular weight: 51720.20 Da Isoelectric Point: 5.1789
>NTDB_id=1127291 FGL04_RS03270 WP_007893475.1 590561..591919(+) (vicK) [Streptococcus pseudoporcinus strain NCTC5385]
MTRDIVGNLSLFELAILFLLVFVAIYFIYLAVRDYRNAKIIRQMSHKIRDLINGRYTDDINSKADIELIDLSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRTGQIMMINETAQKQMNISREEALKKNITDLLGSDSPYTYRELVSQTPI
VTLNRRDETGEFITLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTALAVEMTNFTAFMTSILNRFDLVRNQNTVAGKTYEIIRDYPIKS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIRVKMKTTESQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHKGFIWAKSDYGKGSTFTIVLPYDKDVMSDDVDEWEDDID
MTRDIVGNLSLFELAILFLLVFVAIYFIYLAVRDYRNAKIIRQMSHKIRDLINGRYTDDINSKADIELIDLSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRTGQIMMINETAQKQMNISREEALKKNITDLLGSDSPYTYRELVSQTPI
VTLNRRDETGEFITLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTALAVEMTNFTAFMTSILNRFDLVRNQNTVAGKTYEIIRDYPIKS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIRVKMKTTESQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHKGFIWAKSDYGKGSTFTIVLPYDKDVMSDDVDEWEDDID
Nucleotide
Download Length: 1359 bp
>NTDB_id=1127291 FGL04_RS03270 WP_007893475.1 590561..591919(+) (vicK) [Streptococcus pseudoporcinus strain NCTC5385]
ATGACTAGAGACATCGTTGGAAATTTATCTTTATTTGAATTAGCAATACTCTTCTTATTGGTATTTGTTGCTATCTATTT
TATTTATTTAGCTGTTCGCGACTATCGTAATGCTAAAATTATCAGACAGATGAGTCACAAGATTCGTGATTTGATTAACG
GTCGTTATACTGATGATATTAATAGCAAAGCAGATATTGAACTAATTGACTTATCAGAACAACTTAATGATTTGTCAGAT
GTTTTTCGTCTCACTCATGAGAATTTAGCGCAGGAGAAGAATCGTCTGGCTAGTATTTTGGCTTATATGAGTGATGGTGT
TTTAGCGACTGACCGGACTGGTCAGATTATGATGATTAATGAAACAGCACAAAAACAGATGAACATCAGTCGTGAGGAAG
CTCTTAAAAAAAATATCACCGATCTCTTGGGGAGTGATTCTCCTTATACTTATAGAGAATTAGTGTCCCAAACACCAATT
GTTACCCTAAACCGTCGTGATGAGACAGGTGAATTTATCACACTTCGCTTACGCTTTGCTTTGAATCGACGTGAAAGTGG
CTTTATTTCAGGCTTGGTTGTCGTATTGCACGACACCACTGAACAAGAAAAAGAAGAAAGGGAGCGCCGTCTCTTCGTTT
CCAACGTTAGCCATGAGCTAAGAACCCCTTTGACTTCTGTTAAATCTTATCTAGAAGCGCTTGATGAAGGAGCTTTAAAA
GAAGATATTGCTCCAAGTTTTATCAAAGTGTCTCTTGATGAAACCAACCGTATGATGCGGATGATTTCTGATCTTTTGAA
TTTATCACGAATTGACAATCAAGTGACAGCCTTAGCTGTTGAAATGACTAATTTTACAGCTTTTATGACGTCAATCTTAA
ATCGTTTTGATTTGGTTCGTAATCAAAATACGGTTGCTGGCAAAACTTATGAAATCATTCGTGATTATCCCATAAAGTCA
ATTTGGTTAGAAATTGATAATGATAAGATGACCCAGGTTATTGAAAATATCCTAAATAATGCTATTAAATACTCCCCTGA
TGGTGGTAAAATCCGAGTTAAAATGAAGACTACGGAGAGTCAGCTAATTATTTCCATTTCCGACCAAGGTTTGGGGATTC
CTAAAAAAGATCTCCCTTTAATCTTCGACCGTTTTTATCGTGTTGATAAAGCACGCAGTCGGGCACAGGGTGGAACAGGG
CTGGGATTAGCTATTGCAAAAGAGATTGTTAAACAACATAAGGGCTTTATTTGGGCTAAAAGTGATTATGGTAAAGGTTC
GACCTTTACAATTGTTCTTCCTTATGACAAAGATGTAATGTCAGATGATGTTGATGAATGGGAGGACGATATTGATTAA
ATGACTAGAGACATCGTTGGAAATTTATCTTTATTTGAATTAGCAATACTCTTCTTATTGGTATTTGTTGCTATCTATTT
TATTTATTTAGCTGTTCGCGACTATCGTAATGCTAAAATTATCAGACAGATGAGTCACAAGATTCGTGATTTGATTAACG
GTCGTTATACTGATGATATTAATAGCAAAGCAGATATTGAACTAATTGACTTATCAGAACAACTTAATGATTTGTCAGAT
GTTTTTCGTCTCACTCATGAGAATTTAGCGCAGGAGAAGAATCGTCTGGCTAGTATTTTGGCTTATATGAGTGATGGTGT
TTTAGCGACTGACCGGACTGGTCAGATTATGATGATTAATGAAACAGCACAAAAACAGATGAACATCAGTCGTGAGGAAG
CTCTTAAAAAAAATATCACCGATCTCTTGGGGAGTGATTCTCCTTATACTTATAGAGAATTAGTGTCCCAAACACCAATT
GTTACCCTAAACCGTCGTGATGAGACAGGTGAATTTATCACACTTCGCTTACGCTTTGCTTTGAATCGACGTGAAAGTGG
CTTTATTTCAGGCTTGGTTGTCGTATTGCACGACACCACTGAACAAGAAAAAGAAGAAAGGGAGCGCCGTCTCTTCGTTT
CCAACGTTAGCCATGAGCTAAGAACCCCTTTGACTTCTGTTAAATCTTATCTAGAAGCGCTTGATGAAGGAGCTTTAAAA
GAAGATATTGCTCCAAGTTTTATCAAAGTGTCTCTTGATGAAACCAACCGTATGATGCGGATGATTTCTGATCTTTTGAA
TTTATCACGAATTGACAATCAAGTGACAGCCTTAGCTGTTGAAATGACTAATTTTACAGCTTTTATGACGTCAATCTTAA
ATCGTTTTGATTTGGTTCGTAATCAAAATACGGTTGCTGGCAAAACTTATGAAATCATTCGTGATTATCCCATAAAGTCA
ATTTGGTTAGAAATTGATAATGATAAGATGACCCAGGTTATTGAAAATATCCTAAATAATGCTATTAAATACTCCCCTGA
TGGTGGTAAAATCCGAGTTAAAATGAAGACTACGGAGAGTCAGCTAATTATTTCCATTTCCGACCAAGGTTTGGGGATTC
CTAAAAAAGATCTCCCTTTAATCTTCGACCGTTTTTATCGTGTTGATAAAGCACGCAGTCGGGCACAGGGTGGAACAGGG
CTGGGATTAGCTATTGCAAAAGAGATTGTTAAACAACATAAGGGCTTTATTTGGGCTAAAAGTGATTATGGTAAAGGTTC
GACCTTTACAATTGTTCTTCCTTATGACAAAGATGTAATGTCAGATGATGTTGATGAATGGGAGGACGATATTGATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| vicK | Streptococcus mutans UA159 |
72.947 |
91.593 |
0.668 |
| micB | Streptococcus pneumoniae Cp1015 |
66.353 |
94.027 |
0.624 |