Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FGL00_RS02905 Genome accession   NZ_LR594034
Coordinates   546950..547660 (+) Length   236 a.a.
NCBI ID   WP_138098294.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 541950..552660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS02880 (NCTC8546_00591) - 542630..543625 (+) 996 WP_003057220.1 DUF3114 domain-containing protein -
  FGL00_RS02885 (NCTC8546_00592) - 543721..544368 (-) 648 WP_138083734.1 amino acid ABC transporter permease -
  FGL00_RS02890 (NCTC8546_00593) - 544383..545084 (-) 702 WP_012766679.1 amino acid ABC transporter permease -
  FGL00_RS02895 (NCTC8546_00594) - 545098..545898 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  FGL00_RS02900 - 545898..546691 (-) 794 Protein_511 amino acid ABC transporter ATP-binding protein -
  FGL00_RS02905 (NCTC8546_00597) vicR 546950..547660 (+) 711 WP_138098294.1 response regulator YycF Regulator
  FGL00_RS02910 (NCTC8546_00598) vicK 547653..549005 (+) 1353 WP_138098296.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL00_RS02915 (NCTC8546_00599) vicX 549009..549818 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  FGL00_RS02920 (NCTC8546_00600) rnc 550576..551268 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27061.94 Da        Isoelectric Point: 5.0023

>NTDB_id=1127237 FGL00_RS02905 WP_138098294.1 546950..547660(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MKKILIVDDEKTISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1127237 FGL00_RS02905 WP_138098294.1 546950..547660(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGAAAAAAATACTGATTGTGGATGATGAAAAAACGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCATTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment