Detailed information NTG1127152

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FGK99_RS00280
• Genome accession: NZ_LR594033
• Coordinates: 47847..48761 (+)
• Length: 304 a.a.
• NCBI ID: WP_042669756.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC4675
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42847..53761

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK99_RS00260 (NCTC4675_00052)	purE	43872..44360 (+)	489	WP_021320238.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
FGK99_RS00265 (NCTC4675_00053)	purK	44347..45420 (+)	1074	WP_138118619.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FGK99_RS00270 (NCTC4675_00054)	-	45435..45659 (+)	225	WP_012677202.1	hypothetical protein	-
FGK99_RS00275 (NCTC4675_00055)	purB	46256..47548 (+)	1293	WP_111710074.1	adenylosuccinate lyase	-
FGK99_RS00280 (NCTC4675_00056)	comR	47847..48761 (+)	915	WP_042669756.1	helix-turn-helix domain-containing protein	Regulator
FGK99_RS10225 (NCTC4675_00057)	comS	48844..48942 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
FGK99_RS00285 (NCTC4675_00058)	ruvB	48976..49977 (+)	1002	WP_042669757.1	Holliday junction branch migration DNA helicase RuvB	-
FGK99_RS00290 (NCTC4675_00059)	-	50225..50683 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
FGK99_RS00295 (NCTC4675_00060)	-	50689..51090 (+)	402	WP_138118621.1	hypothetical protein	-
FGK99_RS00300 (NCTC4675_00061)	-	51087..52868 (+)	1782	WP_138118623.1	acyltransferase family protein	-
FGK99_RS00305	-	53057..53251 (+)	195	WP_138118625.1	hypothetical protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35806.34 Da
• Isoelectric Point: 4.5517

>NTDB_id=1127152 FGK99_RS00280 WP_042669756.1 47847..48761(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=1127152 FGK99_RS00280 WP_042669756.1 47847..48761(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTGTTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis D9	37.874	99.013	0.375
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis P1/7	38.644	97.039	0.375