Detailed information NTG1127048

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: FGK91_RS04830
• Genome accession: NZ_LR590483
• Coordinates: 923161..923997 (+)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8318
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 918161..928997

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK91_RS04800 (NCTC8318_00954)	-	918649..919083 (+)	435	WP_023079442.1	hypothetical protein	-
FGK91_RS04805 (NCTC8318_00955)	-	919133..920044 (-)	912	WP_023079407.1	diacylglycerol kinase family protein	-
FGK91_RS04810 (NCTC8318_00956)	-	920161..920811 (-)	651	WP_023079408.1	hemolysin III family protein	-
FGK91_RS04815 (NCTC8318_00957)	-	920808..921248 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
FGK91_RS04820 (NCTC8318_00958)	ylqF	921467..922315 (+)	849	WP_023612970.1	ribosome biogenesis GTPase YlqF	-
FGK91_RS04825 (NCTC8318_00959)	-	922305..923096 (+)	792	WP_023079417.1	ribonuclease HII	-
FGK91_RS04830 (NCTC8318_00960)	dprA	923161..923997 (+)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
FGK91_RS04835 (NCTC8318_00961)	topA	924105..926234 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
FGK91_RS09305	-	926309..927193 (-)	885	Protein_883	LysR family transcriptional regulator	-
FGK91_RS04850 (NCTC8318_00963)	-	927206..927759 (+)	554	Protein_884	PTS sugar transporter subunit IIC	-
FGK91_RS04855 (NCTC8318_00964)	-	927774..928766 (+)	993	WP_023078604.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=1127048 FGK91_RS04830 WP_023079425.1 923161..923997(+) (dprA) [Streptococcus pyogenes strain NCTC8318]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1127048 FGK91_RS04830 WP_023079425.1 923161..923997(+) (dprA) [Streptococcus pyogenes strain NCTC8318]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367