Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EL267_RS00235 Genome accession   NZ_LR134520
Coordinates   33034..34263 (-) Length   409 a.a.
NCBI ID   WP_000728357.1    Uniprot ID   A0AAD2WWM9
Organism   Streptococcus agalactiae strain NCTC13947     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28034..39263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL267_RS00210 (NCTC13947_00039) - 28145..28342 (-) 198 WP_000285199.1 DUF951 domain-containing protein -
  EL267_RS00215 (NCTC13947_00040) - 28352..29244 (-) 893 Protein_12 diacylglycerol/lipid kinase family protein -
  EL267_RS00220 (NCTC13947_00042) dnaN 29302..30438 (-) 1137 WP_000581132.1 DNA polymerase III subunit beta -
  EL267_RS00225 (NCTC13947_00043) dnaA 30593..31954 (-) 1362 WP_000138202.1 chromosomal replication initiator protein DnaA -
  EL267_RS00230 (NCTC13947_00044) spo0J 32163..32936 (-) 774 WP_000456084.1 ParB/RepB/Spo0J family partition protein Regulator
  EL267_RS00235 (NCTC13947_00045) htrA 33034..34263 (-) 1230 WP_000728357.1 S1C family serine protease Regulator
  EL267_RS00240 (NCTC13947_00046) rlmH 34464..34943 (+) 480 WP_000768335.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EL267_RS00260 (NCTC13947_00050) - 35524..38103 (-) 2580 WP_000154433.1 YfhO family protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 43090.54 Da        Isoelectric Point: 9.5271

>NTDB_id=1123793 EL267_RS00235 WP_000728357.1 33034..34263(-) (htrA) [Streptococcus agalactiae strain NCTC13947]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1123793 EL267_RS00235 WP_000728357.1 33034..34263(-) (htrA) [Streptococcus agalactiae strain NCTC13947]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

PDZ domain (PDZ_2)

(300-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.359

96.088

0.609
  htrA Streptococcus gordonii str. Challis substr. CH1

57.357

98.044

0.562
  htrA Streptococcus mitis NCTC 12261

56.533

97.311

0.55
  htrA Streptococcus pneumoniae TIGR4

55.037

99.511

0.548
  htrA Streptococcus pneumoniae Rx1

55.037

99.511

0.548
  htrA Streptococcus pneumoniae D39

55.037

99.511

0.548
  htrA Streptococcus pneumoniae R6

55.037

99.511

0.548

Multiple sequence alignment