Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EL215_RS00265 Genome accession   NZ_LR134481
Coordinates   51900..53123 (+) Length   407 a.a.
NCBI ID   WP_126469445.1    Uniprot ID   A0A448PX25
Organism   Haemophilus parainfluenzae strain NCTC10665     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 46900..58123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL215_RS00235 (NCTC10665_00046) - 47488..48282 (-) 795 WP_126469435.1 sulfite exporter TauE/SafE family protein -
  EL215_RS00240 (NCTC10665_00047) rppH 48413..48875 (-) 463 Protein_46 RNA pyrophosphohydrolase -
  EL215_RS00250 (NCTC10665_00048) ampD 49360..49923 (-) 564 WP_126469439.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  EL215_RS00255 (NCTC10665_00049) pilA 50065..50502 (+) 438 WP_126469441.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  EL215_RS00260 (NCTC10665_00050) pilB 50509..51891 (+) 1383 WP_126469443.1 GspE/PulE family protein Machinery gene
  EL215_RS00265 (NCTC10665_00051) pilC 51900..53123 (+) 1224 WP_126469445.1 type II secretion system F family protein Machinery gene
  EL215_RS00270 (NCTC10665_00052) pilD 53120..53797 (+) 678 WP_126469447.1 prepilin peptidase Machinery gene
  EL215_RS00275 (NCTC10665_00053) coaE 53883..54503 (+) 621 WP_126469449.1 dephospho-CoA kinase -
  EL215_RS00280 (NCTC10665_00054) yacG 54496..54702 (+) 207 WP_126469451.1 DNA gyrase inhibitor YacG -
  EL215_RS00285 (NCTC10665_00055) - 54699..54980 (+) 282 WP_126469453.1 GNAT family N-acetyltransferase -
  EL215_RS00290 (NCTC10665_00056) rhlB 55071..56330 (+) 1260 WP_126469455.1 ATP-dependent RNA helicase RhlB -
  EL215_RS00295 (NCTC10665_00057) mreD 56371..56859 (-) 489 WP_126469457.1 rod shape-determining protein MreD -
  EL215_RS00300 (NCTC10665_00058) mreC 56859..57923 (-) 1065 WP_049357720.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46147.64 Da        Isoelectric Point: 9.6102

>NTDB_id=1123023 EL215_RS00265 WP_126469445.1 51900..53123(+) (pilC) [Haemophilus parainfluenzae strain NCTC10665]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFLLIAKGFSHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLSALIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQHHFVALMIACSFAIFMLKMALKHSLW
LNQKKNALISRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLQHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=1123023 EL215_RS00265 WP_126469445.1 51900..53123(+) (pilC) [Haemophilus parainfluenzae strain NCTC10665]
ATGGCAAAGCAAAAACTCTTTTATTTCCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGTAGCCTTGTTGCTCAATC
TAAACAAGCCGCACAATTTCTGTTAATTGCAAAAGGTTTTAGTCACATTCGCTTGCAACAAGATTGGCAACTTAATCAGA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAACTGGCTACATTGCTCAGTTCTGCCATTCCATTAAAAAATGCA
TTACATATTTTGCAAGACAACTGCACGCAATTGGGATTACATCAGTGGCTTAGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGCTTGGAAATACAAGGAAAGTATTTAAACTTTCAAGAGATTCAACTTATTCAAGTGGGAGAAA
TGACCGGAAAACTGGCAGAGGTATGCACTAAAATTGCAGAACGTCGAACGCAATCATTAACGCTTCAACGCAAATTGCAA
AAAATTATGCTTTATCCTGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTCGTTGTACCTCA
ATTTGCTGAAATGTATGGTGAAAATTCCGCTGAATTGCCTACATTAACTGCCGTATTATTAGCTATGTCTCAATTCCTAC
AACATCATTTTGTTGCGTTAATGATTGCCTGCTCTTTCGCTATTTTTATGTTGAAGATGGCATTAAAACATTCCCTTTGG
CTAAATCAAAAAAAGAATGCACTAATTAGCCGCATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGCCTAATCAGTTT
TAGCCATAACCTCCAATTAATGCTTCAATCCGGAGTGGCATTAACGCCAGCCTTAAATAGCTTCCTCCCCAAACAACAAA
CCTGGCAAACACAACGTACCTTAAAAGGTGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCGCAA
GGTTATCCATTTTCAGAAAGTGTCAGTAGTCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAAAAAAG
TGGAAAACTCGCATTGATGTTGCAACATATTGCCGATAACTATCAAGAAAAACTCAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATTGGTATCATAATGATGGGCATGTATCTGCCGATTTTT
AATATGGGATCCGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448PX25

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.802

99.263

0.693
  pilC Haemophilus influenzae 86-028NP

69.059

99.263

0.685
  pilC Glaesserella parasuis strain SC1401

40.15

98.526

0.396

Multiple sequence alignment