Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   EL190_RS03465 Genome accession   NZ_LR134395
Coordinates   660850..662187 (+) Length   445 a.a.
NCBI ID   WP_006995132.1    Uniprot ID   -
Organism   Haemophilus aegyptius strain NCTC8134     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 655850..667187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL190_RS03440 (NCTC8134_00698) - 655909..658509 (-) 2601 WP_006995137.1 penicillin-binding protein 1A -
  EL190_RS03445 (NCTC8134_00700) - 658608..659405 (+) 798 Protein_660 competence protein ComA -
  EL190_RS03450 (NCTC8134_00701) comB 659406..659912 (+) 507 WP_006995134.1 competence protein ComB Machinery gene
  EL190_RS03455 (NCTC8134_00702) comC 659909..660430 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  EL190_RS03460 (NCTC8134_00703) comD 660427..660840 (+) 414 WP_006995133.1 pilus assembly protein PilP Machinery gene
  EL190_RS03465 (NCTC8134_00704) comE 660850..662187 (+) 1338 WP_006995132.1 type IV pilus secretin PilQ Machinery gene
  EL190_RS03470 (NCTC8134_00705) - 662200..662886 (+) 687 WP_006995131.1 ComF family protein -
  EL190_RS03475 (NCTC8134_00706) nfuA 662962..663558 (+) 597 WP_006995130.1 Fe-S biogenesis protein NfuA -
  EL190_RS03480 nudC 663625..664420 (+) 796 Protein_667 NAD(+) diphosphatase -
  EL190_RS03485 (NCTC8134_00709) - 664456..665046 (+) 591 WP_006995127.1 YjaG family protein -
  EL190_RS03490 (NCTC8134_00710) - 665186..665458 (+) 273 WP_006995126.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49084.31 Da        Isoelectric Point: 8.2628

>NTDB_id=1122725 EL190_RS03465 WP_006995132.1 660850..662187(+) (comE) [Haemophilus aegyptius strain NCTC8134]
MKKYLLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSTGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEGVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=1122725 EL190_RS03465 WP_006995132.1 660850..662187(+) (comE) [Haemophilus aegyptius strain NCTC8134]
ATGAAGAAATATCTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACACTGGAGCAATTAGCTTTCCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTTCTACGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCATTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGTACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGGGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.876

100

0.989
  comE Haemophilus influenzae Rd KW20

97.303

100

0.973
  comE Glaesserella parasuis strain SC1401

52.235

95.506

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.584

0.391
  pilQ Vibrio cholerae strain A1552

42.233

92.584

0.391

Multiple sequence alignment