Detailed information NTG1121989

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL147_RS01165
• Genome accession: NZ_LR134341
• Coordinates: 232241..233080 (-)
• Length: 279 a.a.
• NCBI ID: WP_007891462.1
• Uniprot ID: G5KBW4
• Organism: Streptococcus pseudoporcinus strain NCTC13786
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 227241..238080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL147_RS01150 (NCTC13786_00229)	-	227449..228507 (-)	1059	WP_007891351.1	PTS transporter subunit IIC	-
EL147_RS01155 (NCTC13786_00230)	-	228717..229601 (+)	885	WP_007891151.1	LysR family transcriptional regulator	-
EL147_RS01160 (NCTC13786_00231)	topA	230005..232137 (-)	2133	WP_007891355.1	type I DNA topoisomerase	-
EL147_RS01165 (NCTC13786_00232)	dprA	232241..233080 (-)	840	WP_007891462.1	DNA-processing protein DprA	Machinery gene
EL147_RS01170 (NCTC13786_00233)	-	233153..233701 (-)	549	WP_007891429.1	sugar O-acetyltransferase	-
EL147_RS01175 (NCTC13786_00234)	-	233748..234521 (-)	774	WP_007891277.1	ribonuclease HII	-
EL147_RS01180 (NCTC13786_00235)	ylqF	234496..235359 (-)	864	WP_007891343.1	ribosome biogenesis GTPase YlqF	-
EL147_RS01185 (NCTC13786_00236)	-	235538..235966 (+)	429	WP_007891337.1	DUF1836 domain-containing protein	-
EL147_RS01190 (NCTC13786_00237)	-	235980..236630 (+)	651	WP_007891140.1	hemolysin III family protein	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31113.95 Da
• Isoelectric Point: 9.1664

>NTDB_id=1121989 EL147_RS01165 WP_007891462.1 232241..233080(-) (dprA) [Streptococcus pseudoporcinus strain NCTC13786]
MNNFELYKLRKAGLKNHHILNVINYYQTYGKSLSLRNMAVASETSDPIQFIETYKTIDSKALRKEFNQYPSISLLDKNYP
SLLKEIYNPPVLLFYQGDLELLNYPKLAVVGSRKSSPLGLKVTQKIIEELNNKLIIVSGLARGVDTAAHCCALKTGGRTI
AVIGSGFNHYYPKENQRLQKFIASNHLLLTEYGPNDPPLSIHFPERNRIIAGLVKAVLVIEAKSRSGSLITCRYALENGR
EVFAVPGNISDSFSDGCNQLIQEGAKCIMSGLDVLTELF

Nucleotide

• Length: 840 bp

>NTDB_id=1121989 EL147_RS01165 WP_007891462.1 232241..233080(-) (dprA) [Streptococcus pseudoporcinus strain NCTC13786]
ATGAATAATTTTGAACTTTACAAACTTCGAAAAGCAGGTTTGAAAAACCATCACATTTTAAATGTCATTAATTATTACCA
AACTTATGGTAAATCCCTATCTTTACGGAATATGGCGGTCGCTTCTGAGACATCAGATCCTATACAATTTATTGAAACTT
ATAAAACAATTGATAGTAAAGCTCTGCGGAAAGAATTTAATCAGTATCCTAGTATTTCCCTCCTTGATAAAAATTATCCC
TCGCTTTTAAAAGAAATCTATAATCCACCGGTTTTGCTTTTTTATCAAGGAGATTTAGAACTTTTAAATTATCCAAAACT
AGCGGTGGTAGGCTCCCGCAAATCTAGTCCATTAGGTTTAAAAGTAACTCAAAAAATAATAGAAGAATTAAATAATAAAC
TTATTATTGTCAGTGGACTTGCTAGAGGTGTCGATACTGCGGCACACTGTTGTGCGCTTAAAACGGGTGGTCGTACAATT
GCTGTCATTGGCTCGGGTTTCAATCATTATTACCCTAAAGAAAACCAGAGGTTGCAAAAATTTATTGCGTCTAATCACCT
TTTATTAACAGAATATGGCCCAAATGATCCTCCTTTATCTATTCATTTTCCAGAGAGGAATCGGATTATTGCTGGCCTAG
TTAAAGCAGTGCTAGTTATTGAAGCTAAAAGCCGGTCTGGAAGTTTAATAACATGCCGGTACGCCCTTGAAAATGGTCGC
GAAGTTTTTGCTGTTCCTGGAAATATTAGCGATAGTTTTTCCGATGGTTGTAATCAACTTATCCAAGAAGGTGCAAAGTG
CATCATGAGTGGTTTGGATGTGCTTACAGAACTTTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: G5KBW4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	64.029	99.642	0.638
dprA/cilB/dalA	Streptococcus mitis SK321	56.475	99.642	0.563
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	56.115	99.642	0.559
dprA/cilB/dalA	Streptococcus pneumoniae D39	56.115	99.642	0.559
dprA/cilB/dalA	Streptococcus pneumoniae R6	56.115	99.642	0.559
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	56.115	99.642	0.559
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	55.755	99.642	0.556
dprA	Lactococcus lactis subsp. cremoris KW2	51.264	99.283	0.509
dprA	Bacillus subtilis subsp. subtilis str. 168	42.857	90.323	0.387
dprA	Legionella pneumophila strain ERS1305867	42.798	87.097	0.373