Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EL140_RS09395 Genome accession   NZ_LR134336
Coordinates   1898385..1899047 (-) Length   220 a.a.
NCBI ID   WP_000995723.1    Uniprot ID   A0A081R3Z6
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1893385..1904047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS09375 (NCTC11427_01854) rplI 1893929..1894381 (-) 453 WP_000864211.1 50S ribosomal protein L9 -
  EL140_RS09380 (NCTC11427_01855) - 1894378..1896351 (-) 1974 WP_000739979.1 DHH family phosphoesterase -
  EL140_RS09385 (NCTC11427_01856) - 1896497..1897675 (-) 1179 WP_000656055.1 acetyl-CoA C-acetyltransferase -
  EL140_RS09390 (NCTC11427_01857) hpf 1897757..1898305 (-) 549 WP_000599114.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL140_RS09395 (NCTC11427_01858) comFC/cflB 1898385..1899047 (-) 663 WP_000995723.1 ComF family protein Machinery gene
  EL140_RS09400 (NCTC11427_01859) comFA/cflA 1899044..1900342 (-) 1299 WP_000867712.1 DEAD/DEAH box helicase Machinery gene
  EL140_RS09405 (NCTC11427_01860) - 1900399..1901034 (+) 636 WP_000395765.1 YigZ family protein -
  EL140_RS09410 (NCTC11427_01861) - 1901049..1901492 (+) 444 WP_000863903.1 PH domain-containing protein -
  EL140_RS09415 (NCTC11427_01862) cysK 1901589..1902515 (+) 927 WP_001029449.1 cysteine synthase A -
  EL140_RS09420 (NCTC11427_01863) tsf 1902619..1903659 (-) 1041 WP_000808057.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25020.01 Da        Isoelectric Point: 8.1493

>NTDB_id=1121874 EL140_RS09395 WP_000995723.1 1898385..1899047(-) (comFC/cflB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MNCLLCGQTTKSELTFSSLFLLKDDCSYLCSACASSFERIGENYCPNCMKTGMSTKCQDCKLWCKEGIQVDHKAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASVLAEELKKYRGYQFVLIPLSPERLLERGFNQVEGLVEATGFSFKDILGKREESASSS
KSRLERLATEIPFFIKDGISFPKKILLIDDIYTTGATVNRVKRLLEEAGALEVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1121874 EL140_RS09395 WP_000995723.1 1898385..1899047(-) (comFC/cflB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAACTGTTTATTATGTGGCCAGACTACAAAGAGTGAGCTGACTTTTAGCAGTCTCTTCCTTTTGAAGGATGATTGCAG
TTATCTTTGCTCAGCTTGTGCTTCTAGTTTTGAGAGGATTGGTGAGAATTATTGCCCAAACTGTATGAAAACAGGCATGT
CAACTAAGTGTCAAGATTGTAAACTTTGGTGTAAAGAAGGAATTCAGGTTGATCATAAGGCAATCTTTACCTATAATCAA
GCTATGAAAGACTTTTTCAGTCGATATAAGTTTGATGGCGATTTTTTGCTTAGAAAGGTTTTTGCTTCTGTTCTTGCTGA
GGAGCTGAAAAAGTATAGAGGATATCAATTTGTGTTGATTCCCCTAAGCCCTGAAAGATTGCTTGAGAGGGGGTTTAACC
AAGTCGAAGGTTTGGTTGAGGCAACAGGCTTTTCTTTTAAAGATATATTAGGAAAAAGAGAAGAGAGCGCTAGTTCTTCT
AAAAGCCGTTTGGAAAGGTTAGCTACTGAAATTCCATTTTTTATTAAAGATGGTATCTCATTTCCTAAGAAGATTTTGCT
GATTGATGACATCTATACAACAGGGGCAACTGTGAATCGTGTGAAACGACTTTTGGAAGAAGCAGGTGCTTTGGAAGTTA
AAACTTTTTCCCTTGTAAGATAA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(183-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A081R3Z6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

79.091

100

0.791
  comFC/cflB Streptococcus mitis SK321

78.182

100

0.782
  comFC/cflB Streptococcus pneumoniae D39

77.727

100

0.777
  comFC/cflB Streptococcus pneumoniae R6

77.727

100

0.777
  comFC/cflB Streptococcus pneumoniae Rx1

77.727

100

0.777
  comFC/cflB Streptococcus pneumoniae TIGR4

77.727

100

0.777
  comFC Bacillus subtilis subsp. subtilis str. 168

36.564

100

0.377

Multiple sequence alignment