Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL140_RS09400 Genome accession   NZ_LR134336
Coordinates   1899044..1900342 (-) Length   432 a.a.
NCBI ID   WP_000867712.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1894044..1905342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS09380 (NCTC11427_01855) - 1894378..1896351 (-) 1974 WP_000739979.1 DHH family phosphoesterase -
  EL140_RS09385 (NCTC11427_01856) - 1896497..1897675 (-) 1179 WP_000656055.1 acetyl-CoA C-acetyltransferase -
  EL140_RS09390 (NCTC11427_01857) hpf 1897757..1898305 (-) 549 WP_000599114.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL140_RS09395 (NCTC11427_01858) comFC/cflB 1898385..1899047 (-) 663 WP_000995723.1 ComF family protein Machinery gene
  EL140_RS09400 (NCTC11427_01859) comFA/cflA 1899044..1900342 (-) 1299 WP_000867712.1 DEAD/DEAH box helicase Machinery gene
  EL140_RS09405 (NCTC11427_01860) - 1900399..1901034 (+) 636 WP_000395765.1 YigZ family protein -
  EL140_RS09410 (NCTC11427_01861) - 1901049..1901492 (+) 444 WP_000863903.1 PH domain-containing protein -
  EL140_RS09415 (NCTC11427_01862) cysK 1901589..1902515 (+) 927 WP_001029449.1 cysteine synthase A -
  EL140_RS09420 (NCTC11427_01863) tsf 1902619..1903659 (-) 1041 WP_000808057.1 translation elongation factor Ts -
  EL140_RS09425 (NCTC11427_01864) rpsB 1903738..1904517 (-) 780 WP_000268475.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49538.43 Da        Isoelectric Point: 8.1608

>NTDB_id=1121875 EL140_RS09400 WP_000867712.1 1899044..1900342(-) (comFA/cflA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKVNPNYLGRLFTEKELTKEECQMAEKLPAMRKEKGKLFCQRCNSSILEEWHLPIGAYYCRECLLMKRVRSDQALYYFSQ
EDFPKQDVLKWRGQLTPFQEKLSEGLIRAVEKKEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVIATTHQLLKFYHAFDLLIVDEVDAFPYVDNSMLYYAVKNSVKEDGLRIFLTATST
DELDRKVHTGELKRLSLPRRFHGNPLIIPKPVWLSDFNHCLEKSQLSSKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LKEQYPNENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1121875 EL140_RS09400 WP_000867712.1 1899044..1900342(-) (comFA/cflA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACAAAAGAAGAATGTCAGATGGCTGAGAA
ACTTCCAGCAATGAGAAAAGAGAAAGGGAAACTGTTTTGTCAACGTTGTAATAGTAGTATTCTAGAAGAATGGCATTTGC
CTATTGGTGCCTACTATTGTAGGGAGTGTTTGCTGATGAAGCGAGTCAGGAGTGATCAAGCCTTATACTATTTTTCGCAG
GAAGATTTTCCAAAGCAAGATGTTCTCAAATGGCGTGGTCAGTTAACCCCTTTTCAGGAAAAGTTATCAGAGGGGTTGAT
TCGAGCAGTCGAAAAGAAAGAACCGACTTTAGTTCATGCTGTGACGGGTGCTGGAAAGACAGAGATGATTTATCAAGTTG
TAGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCAAGCCCTAGAATTGATGTATGTTTAGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGTGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCTTAGTAATTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ATAACTCTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTAAGGATATTCCTTACAGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCACACAGGAGAATTAAAACGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCACTGTTTAGAGAAAAGTCAGTTGTCATCCAAGTTAAAGACCTACA
TTGAGAAACAGAGAAGAACAGGTTATCCTTTGCTGATTTTTGCATCAGAGATTAAAAAAGGCGAGAAACTAAAAGAAATC
TTGAAGGAGCAGTACCCGAATGAGAATATCGGATTTGTGTCTTCTGTCACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATCTTGGAACGCGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGTTTGATTCAGATTGGAGGGCGAGTTGGACGCAGTATGGATAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATGCTTCCATCAAAAAGGCAATCAAGGAAATCAAGCAGATGAA
TAAGGAGGCAGGGTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(291-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.046

100

0.9
  comFA/cflA Streptococcus mitis SK321

89.12

100

0.891
  comFA/cflA Streptococcus pneumoniae Rx1

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae D39

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae R6

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae TIGR4

88.426

100

0.884
  comFA Lactococcus lactis subsp. cremoris KW2

50.735

94.444

0.479
  comFA Latilactobacillus sakei subsp. sakei 23K

38.813

100

0.394

Multiple sequence alignment