Detailed information NTG1121851

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: EL140_RS05455
• Genome accession: NZ_LR134336
• Coordinates: 1076481..1077329 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705328.1
• Uniprot ID: -
• Organism: Streptococcus oralis ATCC 35037 strain NCTC 11427
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1071481..1082329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL140_RS05435 (NCTC11427_01072)	-	1072384..1073040 (-)	657	WP_000461558.1	MmcQ/YjbR family DNA-binding protein	-
EL140_RS05440 (NCTC11427_01073)	-	1073084..1073716 (-)	633	WP_000638807.1	copper homeostasis protein CutC	-
EL140_RS05445 (NCTC11427_01074)	-	1073810..1074169 (-)	360	WP_001220358.1	YbaN family protein	-
EL140_RS05450 (NCTC11427_01075)	topA	1074276..1076363 (-)	2088	WP_000179670.1	type I DNA topoisomerase	-
EL140_RS05455 (NCTC11427_01076)	dprA/cilB/dalA	1076481..1077329 (-)	849	WP_000705328.1	DNA-processing protein DprA	Machinery gene
EL140_RS05460 (NCTC11427_01077)	-	1077410..1078033 (-)	624	WP_000734769.1	hypothetical protein	-
EL140_RS05465 (NCTC11427_01078)	lepA	1078174..1079997 (-)	1824	WP_001047193.1	translation elongation factor 4	-
EL140_RS05470 (NCTC11427_01079)	-	1080076..1080804 (-)	729	WP_000133347.1	metallophosphoesterase family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31245.73 Da
• Isoelectric Point: 5.2027

>NTDB_id=1121851 EL140_RS05455 WP_000705328.1 1076481..1077329(-) (dprA/cilB/dalA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKITNYEIYKLRKAGLSNQQILTVLEYDETVDQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQKVIQGLENELIVVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=1121851 EL140_RS05455 WP_000705328.1 1076481..1077329(-) (dprA/cilB/dalA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAGATCACAAACTATGAAATTTACAAATTGAGAAAAGCTGGGCTGAGCAATCAACAAATTTTAACAGTTCTTGAATA
CGATGAGACTGTAGATCAGGAGCTCTTGCTAGGTGATATTGCAGAAATATCTGGGTGTCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTTCAGAAATTTCCATCCTTTTCTATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGTGCTCTTGTTTTATAAAGGAAATCTAGACCTGTTGAAATTTCC
AAAGGTTGCTGTTGTAGGGAGTCGTTCATGTTCTAGTCAGGGAGCAAAATCGGTTCAGAAAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTTGTCAGTGGTTTAGCCAAAGGGATTGATACAGCTGCCCATATGGCTGCACTCCAGAATGGAGGAAGA
ACGATTGCCGTCATTGGAACAGGATTGGATGTTTTTTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAGTACGGACCTGGTGAAGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGCATCATTGCTG
GCCTTTGCCGTGGCGTTATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTTATCACCTGTGAGCGAGCTATGGAGGAA
GGGCGTGATGTTTTTGCCATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC
AAAGCTGATTAGCAGTGGCCAAGATGTGTTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	91.489	100	0.915
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae D39	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae R6	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	91.135	100	0.911
dprA/cilB/dalA	Streptococcus mitis SK321	90.426	100	0.904
dprA	Streptococcus mutans UA159	60.714	99.291	0.603
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.291	0.543
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362