Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EL140_RS05125 Genome accession   NZ_LR134336
Coordinates   1010175..1010882 (-) Length   235 a.a.
NCBI ID   WP_000722058.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1005175..1015882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS05110 (NCTC11427_01007) - 1006043..1007914 (-) 1872 WP_000150976.1 Eco57I restriction-modification methylase domain-containing protein -
  EL140_RS05115 (NCTC11427_01008) vicX 1008022..1008831 (-) 810 WP_001290610.1 MBL fold metallo-hydrolase Regulator
  EL140_RS05120 (NCTC11427_01009) micB 1008833..1010182 (-) 1350 WP_000568721.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL140_RS05125 (NCTC11427_01010) micA 1010175..1010882 (-) 708 WP_000722058.1 response regulator YycF Regulator
  EL140_RS05130 (NCTC11427_01011) mutY 1010939..1012117 (-) 1179 WP_000886126.1 A/G-specific adenine glycosylase -
  EL140_RS05135 (NCTC11427_01012) pta 1012200..1013174 (-) 975 WP_000451577.1 phosphate acetyltransferase -
  EL140_RS05140 (NCTC11427_01013) - 1013218..1014114 (-) 897 WP_001210025.1 RluA family pseudouridine synthase -
  EL140_RS05145 (NCTC11427_01014) - 1014111..1014929 (-) 819 WP_000799063.1 NAD kinase -
  EL140_RS05150 (NCTC11427_01015) - 1014913..1015584 (-) 672 WP_000151561.1 GTP pyrophosphokinase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27005.85 Da        Isoelectric Point: 4.6177

>NTDB_id=1121850 EL140_RS05125 WP_000722058.1 1010175..1010882(-) (micA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1121850 EL140_RS05125 WP_000722058.1 1010175..1010882(-) (micA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTCGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCAGAGCAACCAGATATTATTATCCTCGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTATCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGACGATTATGTTACAAAACCTTTCTCAAACCGTGA
ATTGCAGGCTCGTGTCAAGGCCCTGCTTCGTCGTACAGACCTGGTTTCTGTGGATAGCCAAGAGTCTGATGAGAAGAAGA
CGCAACCTTTACAAATTGGTGATTTGGAAATTGTTCCAGATGCTTACGTGGCGAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCGTCTCATATTGGTCAAGTGATTACGCGTGAACATTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACTGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGACA
CTCCAAGTCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment