Detailed information NTG1121566

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: EL134_RS02835
• Genome accession: NZ_LR134325
• Coordinates: 592445..594604 (+)
• Length: 719 a.a.
• NCBI ID: WP_048684925.1
• Uniprot ID: -
• Organism: Lactobacillus paragasseri strain NCTC13720
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 587445..599604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL134_RS02810 (NCTC13720_00575)	udk	587869..588504 (-)	636	WP_003649222.1	uridine kinase	-
EL134_RS02815 (NCTC13720_00576)	-	588666..590033 (+)	1368	WP_048684932.1	MFS transporter	-
EL134_RS02820 (NCTC13720_00577)	-	590176..590328 (+)	153	WP_003649220.1	hypothetical protein	-
EL134_RS02825 (NCTC13720_00578)	-	590355..591638 (+)	1284	WP_232001029.1	GHKL domain-containing protein	-
EL134_RS02830 (NCTC13720_00579)	-	591635..592432 (+)	798	WP_003649217.1	LytR/AlgR family response regulator transcription factor	-
EL134_RS02835 (NCTC13720_00580)	comA	592445..594604 (+)	2160	WP_048684925.1	peptide cleavage/export ABC transporter	Regulator
EL134_RS02840 (NCTC13720_00581)	-	594615..595208 (+)	594	WP_048684922.1	hypothetical protein	-
EL134_RS02850 (NCTC13720_00582)	-	595510..595737 (+)	228	WP_048684917.1	Blp family class II bacteriocin	-
EL134_RS02855 (NCTC13720_00583)	-	595747..595944 (+)	198	WP_003649213.1	Blp family class II bacteriocin	-
EL134_RS02860 (NCTC13720_00584)	-	595960..596298 (+)	339	WP_003649212.1	hypothetical protein	-
EL134_RS09810	-	596507..596653 (+)	147	WP_156235821.1	hypothetical protein	-
EL134_RS02865 (NCTC13720_00586)	-	597020..597304 (+)	285	WP_003649210.1	bacteriocin immunity protein	-
EL134_RS02870 (NCTC13720_00587)	-	597460..597657 (+)	198	WP_003649209.1	hypothetical protein	-
EL134_RS02875 (NCTC13720_00588)	-	597671..597901 (+)	231	WP_003649208.1	hypothetical protein	-
EL134_RS02880 (NCTC13720_00589)	-	598085..598399 (+)	315	WP_003649207.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 719 a.a.
• Molecular weight: 81069.37 Da
• Isoelectric Point: 7.7712

>NTDB_id=1121566 EL134_RS02835 WP_048684925.1 592445..594604(+) (comA) [Lactobacillus paragasseri strain NCTC13720]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENS
IQYPFIAHVLKQGEILHYYVVLKNAKNYLVIADPDPSVGVVKMPKDKFAQEWTGVALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLRYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPIYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIVLWVGAKIVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNRLNEVYQVKSEFNQKATIEDRKL
LEGNIEYKNVDYSYGYGTDVLKDINLKISQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEIDKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDITEEDVIKACQIAEIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKKVIDNLMKLKDKTIIFIAHRLAIAERADKVVVIDHGQIVEEGSHSELMSKHGFYYDLVKG

Nucleotide

• Length: 2160 bp

>NTDB_id=1121566 EL134_RS02835 WP_048684925.1 592445..594604(+) (comA) [Lactobacillus paragasseri strain NCTC13720]
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGCGGCGTTGCTTGTCTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTGAAGACAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGCCCACGTCCTAAAACAAGGAGAAATACTTCATTATTACGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCTGATCCATCAGTTGGTGTAGTAAAGATGCCAAAAGACAAATTTGCTCAAGAATGGACTG
GTGTTGCACTCTTTATGGTTCCTAACGAAGACTTTGAACCAATCAAAGAAAAGAAGAATAATTTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTGATGATTAACATCATTTTAGCCGCTTTATTAATGACCATAATTAGTATCTGTAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTTAATTCAATTTTTTCTTATGGACAGAATTTTTTATTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCGATACATCAGGCATATTTTTGAATTACCAATGGAATTCTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCGCGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGACCTCTCAATTG
TGATTGTGATGGGATTAGTCTTAGCAGCACAAAATATGACATTATTTGGGATTACACTGTTAGCTTTGCCTATTTATGCA
GTTGTAATTCTAGGTTTTACTAAAAAGTTTGAAAAACTAAATAACGAACAAATGGAAAGTAATGCTGTTTTGAGTTCTTC
AGTTATTGAAGATATTCAAGGAATTGAAACTATTAAAGCTTTAAATAGTGAGAATACAAGATATAGAAGAATCGATAGTC
AGTTTGTAGATTACTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTACAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAGATTGTAATGCAAGGACAATTGAGCATTGGTCAGTTAATGAC
GTTCAATGCATTGCTGGCATATTTCATTGATCCCTTGCAAAGTATTATTAATTTACAACCGCGACTTCAATCAGCTAGTG
TTGCTCAAAATCGATTAAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGGCTACTATTGAAGATCGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATAGCTATGGTTATGGCACAGATGTCTTAAAAGATATTAATCTCAA
AATTAGCCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGTTCTGGAAAATCTACGATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAAGGTCAGGTTACATTAAATGGACATGCAACAAGTGAAATTGATAAGCATACGTTGCGGTCATAT
GTAAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAAGAGAATTTGTTGTTAGGTTGTAGGCCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAAATTGCTGAGATTGACCAAGAAATAGCTAATCTACCTTTGCAATTTGAAA
CAAAATTAGATGAAAATGCCAAAATTTTATCTGGTGGACAAAAACAAAGGTTAACTATTGCCCGGGCATTACTATCTCCT
GCAAAGGTATTTATTTTTGATGAAGTAACAAGTGGCTTAGATACAATTACTGAGAAGAAAGTGATTGATAATTTGATGAA
GCTAAAGGATAAGACAATTATCTTTATTGCGCATCGACTAGCAATTGCAGAACGGGCAGACAAGGTAGTTGTAATTGATC
ATGGTCAAATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCATGGTTTTTACTATGACTTAGTGAAGGGATAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-143)

• ABC transporter (ABC_tran) (501-651)

• ABC transporter transmembrane region (ABC_membrane) (169-439)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	57.584	99.026	0.57
comA	Streptococcus mitis SK321	57.303	99.026	0.567
comA	Streptococcus pneumoniae Rx1	57.163	99.026	0.566
comA	Streptococcus pneumoniae D39	57.163	99.026	0.566
comA	Streptococcus pneumoniae R6	57.163	99.026	0.566
comA	Streptococcus pneumoniae TIGR4	57.022	99.026	0.565
comA	Streptococcus gordonii str. Challis substr. CH1	55.337	99.026	0.548
comA/nlmT	Streptococcus mutans UA159	53.607	98.331	0.527