Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   EL133_RS07645 Genome accession   NZ_LR134323
Coordinates   1496799..1497509 (-) Length   236 a.a.
NCBI ID   WP_006740362.1    Uniprot ID   -
Organism   Streptococcus urinalis strain NCTC13766     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1491799..1502509
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS07630 (NCTC13766_01583) rnc 1493839..1494525 (-) 687 WP_006738912.1 ribonuclease III -
  EL133_RS07635 (NCTC13766_01584) vicX 1494644..1495453 (-) 810 WP_006739451.1 MBL fold metallo-hydrolase Regulator
  EL133_RS07640 (NCTC13766_01585) vicK 1495457..1496806 (-) 1350 WP_006738842.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL133_RS07645 (NCTC13766_01586) vicR 1496799..1497509 (-) 711 WP_006740362.1 response regulator YycF Regulator
  EL133_RS07650 (NCTC13766_01587) - 1497816..1498601 (+) 786 WP_006740230.1 amino acid ABC transporter ATP-binding protein -
  EL133_RS07655 (NCTC13766_01588) - 1498611..1499360 (+) 750 WP_006740471.1 transporter substrate-binding domain-containing protein -
  EL133_RS07660 (NCTC13766_01589) - 1499458..1500153 (+) 696 WP_006739051.1 amino acid ABC transporter permease -
  EL133_RS07665 (NCTC13766_01590) - 1500166..1500816 (+) 651 WP_006738599.1 amino acid ABC transporter permease -
  EL133_RS07670 (NCTC13766_01591) - 1500846..1501826 (-) 981 WP_006740273.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27054.81 Da        Isoelectric Point: 5.2608

>NTDB_id=1121541 EL133_RS07645 WP_006740362.1 1496799..1497509(-) (vicR) [Streptococcus urinalis strain NCTC13766]
MKKILIVDDEKPISDIIKFNLAKEGYDTVTAFDGREAIAKFEEENPDLIILDLMLPELDGLEVAKEVRKSSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHIRRNDSITSSSNNDGKASTNSELNIGELQILPEAFVAKKRQKEIE
LTHREFELLHHLANHLGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSNE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1121541 EL133_RS07645 WP_006740362.1 1496799..1497509(-) (vicR) [Streptococcus urinalis strain NCTC13766]
ATGAAAAAAATTCTGATTGTTGATGATGAAAAGCCAATCTCAGATATCATTAAGTTTAATTTAGCTAAAGAAGGGTATGA
TACTGTCACGGCATTTGATGGTCGCGAAGCTATTGCTAAATTTGAAGAAGAAAATCCAGATTTGATTATTTTGGATTTGA
TGTTACCAGAATTAGATGGACTAGAAGTAGCAAAAGAAGTTCGTAAGAGCAGTCATATTCCTATTATTATGCTTTCTGCA
AAGGATAGTGAATTTGATAAGGTGATTGGACTTGAAATTGGTGCAGATGATTATGTGACTAAACCCTTTTCAAATAGAGA
ATTGTTAGCGCGTGTTAAAGCACATATTAGACGTAATGATTCGATTACTTCTTCATCAAATAATGATGGAAAAGCATCAA
CTAACTCTGAACTTAATATTGGAGAACTACAAATTTTACCCGAGGCTTTTGTCGCCAAAAAACGTCAAAAAGAAATTGAA
TTAACTCACCGTGAATTTGAGTTACTTCATCATTTGGCAAACCATCTAGGTCAAGTTATGACGAGAGAACATTTATTAGA
GACTGTTTGGGGTTATGATTATTTTGGTGATGTCAGAACGGTTGATGTTACCGTTCGTCGTCTCCGTGAGAAAATTGAAG
ACACACCAAGCCGTCCTGAATACATTTTGACAAGACGTGGTGTTGGGTATTACATGAAATCAAATGAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(157-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.179

99.153

0.864
  micA Streptococcus pneumoniae Cp1015

75.527

100

0.758
  covR Streptococcus salivarius strain HSISS4

46.121

98.305

0.453
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.064

98.729

0.445

Multiple sequence alignment