Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EL130_RS01620 Genome accession   NZ_LR134320
Coordinates   318661..319575 (-) Length   304 a.a.
NCBI ID   WP_002283788.1    Uniprot ID   A0A829BPJ9
Organism   Streptococcus mutans strain NCTC10832     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 313661..324575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS01610 (NCTC10832_00301) - 315517..315792 (-) 276 WP_002283786.1 hypothetical protein -
  EL130_RS01615 (NCTC10832_00302) - 316289..318130 (+) 1842 WP_002283787.1 carbohydrate-binding domain-containing protein -
  EL130_RS01620 (NCTC10832_00303) comR 318661..319575 (-) 915 WP_002283788.1 helix-turn-helix domain-containing protein Regulator
  EL130_RS01625 (NCTC10832_00304) - 319961..320647 (-) 687 WP_002264678.1 DNA alkylation repair protein -
  EL130_RS01630 (NCTC10832_00305) purB 320667..321965 (-) 1299 WP_002263398.1 adenylosuccinate lyase -
  EL130_RS01635 (NCTC10832_00307) - 322311..323120 (-) 810 WP_002283789.1 GyrI-like domain-containing protein -
  EL130_RS01640 (NCTC10832_00308) - 323202..323402 (-) 201 WP_002283790.1 hypothetical protein -
  EL130_RS01645 (NCTC10832_00309) - 323500..324192 (-) 693 WP_002283791.1 aspartate/glutamate racemase family protein -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35274.41 Da        Isoelectric Point: 4.9127

>NTDB_id=1121402 EL130_RS01620 WP_002283788.1 318661..319575(-) (comR) [Streptococcus mutans strain NCTC10832]
MLKDFGKKIKNLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNEIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=1121402 EL130_RS01620 WP_002283788.1 318661..319575(-) (comR) [Streptococcus mutans strain NCTC10832]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAACCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGTGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGCTTACAATCGAAACTAGATATTCATTTTAGTG
ATAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTCAGCAATGAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(9-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A829BPJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

98.026

100

0.98
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.431

94.737

0.497
  comR Streptococcus pyogenes MGAS315

47.492

98.355

0.467
  comR Streptococcus pyogenes MGAS8232

47.02

99.342

0.467
  comR Streptococcus suis P1/7

43.144

98.355

0.424
  comR Streptococcus suis 05ZYH33

43.144

98.355

0.424
  comR Streptococcus suis D9

37

98.684

0.365

Multiple sequence alignment