Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL130_RS00935 Genome accession   NZ_LR134320
Coordinates   169540..170571 (-) Length   343 a.a.
NCBI ID   WP_255262945.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 164540..175571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS00895 (NCTC10832_00166) - 164718..164963 (-) 246 WP_002278011.1 helix-turn-helix transcriptional regulator -
  EL130_RS00900 (NCTC10832_00167) - 165516..166715 (-) 1200 WP_002265895.1 acetate kinase -
  EL130_RS00905 (NCTC10832_00168) comYH 166774..167727 (-) 954 WP_002278010.1 class I SAM-dependent methyltransferase Machinery gene
  EL130_RS00910 (NCTC10832_00169) comYG 167782..168171 (-) 390 WP_002278009.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL130_RS00915 (NCTC10832_00170) comYF 168149..168583 (-) 435 WP_002264245.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL130_RS00920 (NCTC10832_00171) comYE 168570..168863 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL130_RS00925 (NCTC10832_00172) comYD 168835..169239 (-) 405 WP_002273742.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL130_RS00930 (NCTC10832_00173) comYC 169226..169540 (-) 315 WP_126475429.1 competence type IV pilus major pilin ComGC Machinery gene
  EL130_RS00935 (NCTC10832_00174) comYB 169540..170571 (-) 1032 WP_255262945.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL130_RS00940 (NCTC10832_00175) comYA 170507..171448 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  EL130_RS00945 (NCTC10832_00176) - 171579..171962 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39816.40 Da        Isoelectric Point: 9.5151

>NTDB_id=1121396 EL130_RS00935 WP_255262945.1 169540..170571(-) (comYB) [Streptococcus mutans strain NCTC10832]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVAIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1121396 EL130_RS00935 WP_255262945.1 169540..170571(-) (comYB) [Streptococcus mutans strain NCTC10832]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGCTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.708

100

0.997
  comYB Streptococcus mutans UA140

99.125

100

0.991
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment