Detailed information NTG1121392

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: EL130_RS00915
• Genome accession: NZ_LR134320
• Coordinates: 168149..168583 (-)
• Length: 144 a.a.
• NCBI ID: WP_002264245.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NCTC10832
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 163149..173583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL130_RS00885 (NCTC10832_00164)	-	163594..164256 (-)	663	WP_002263446.1	type II CAAX endopeptidase family protein	-
EL130_RS00890 (NCTC10832_00165)	-	164309..164749 (-)	441	WP_002263445.1	hypothetical protein	-
EL130_RS00895 (NCTC10832_00166)	-	164718..164963 (-)	246	WP_002278011.1	helix-turn-helix transcriptional regulator	-
EL130_RS00900 (NCTC10832_00167)	-	165516..166715 (-)	1200	WP_002265895.1	acetate kinase	-
EL130_RS00905 (NCTC10832_00168)	comYH	166774..167727 (-)	954	WP_002278010.1	class I SAM-dependent methyltransferase	Machinery gene
EL130_RS00910 (NCTC10832_00169)	comYG	167782..168171 (-)	390	WP_002278009.1	competence type IV pilus minor pilin ComGG	Machinery gene
EL130_RS00915 (NCTC10832_00170)	comYF	168149..168583 (-)	435	WP_002264245.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL130_RS00920 (NCTC10832_00171)	comYE	168570..168863 (-)	294	WP_002263439.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL130_RS00925 (NCTC10832_00172)	comYD	168835..169239 (-)	405	WP_002273742.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL130_RS00930 (NCTC10832_00173)	comYC	169226..169540 (-)	315	WP_126475429.1	competence type IV pilus major pilin ComGC	Machinery gene
EL130_RS00935 (NCTC10832_00174)	comYB	169540..170571 (-)	1032	WP_255262945.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL130_RS00940 (NCTC10832_00175)	comYA	170507..171448 (-)	942	WP_002263435.1	competence type IV pilus ATPase ComGA	Machinery gene
EL130_RS00945 (NCTC10832_00176)	-	171579..171962 (-)	384	WP_002263434.1	DUF1033 family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16252.72 Da
• Isoelectric Point: 9.9512

>NTDB_id=1121392 EL130_RS00915 WP_002264245.1 168149..168583(-) (comYF) [Streptococcus mutans strain NCTC10832]
MLKSKLKAFTLLECLLALLVIAGSVSVYNGLTKAISSNIHYLSKNQEDAWLLFCQQFRSELEGTTLQKLDSNKLYVQKNN
QSLAFGKSKASDFRKTNSDGRGYQPMLTEIKAANFSQSGKIIKLDLTFKDGLERTFVYAFHEKN

Nucleotide

• Length: 435 bp

>NTDB_id=1121392 EL130_RS00915 WP_002264245.1 168149..168583(-) (comYF) [Streptococcus mutans strain NCTC10832]
TTGTTAAAAAGTAAATTGAAAGCTTTCACACTTTTAGAGTGTCTCCTTGCTTTGCTTGTCATTGCTGGTAGTGTATCTGT
TTATAATGGTCTAACTAAAGCTATTAGTAGTAATATTCATTACTTATCAAAAAATCAAGAAGATGCTTGGTTACTTTTTT
GTCAGCAATTTCGGTCTGAACTTGAAGGAACGACTTTGCAAAAATTGGATAGCAATAAGCTTTATGTTCAAAAAAATAAT
CAAAGTTTAGCCTTTGGTAAATCAAAAGCAAGTGATTTTAGAAAGACTAACAGTGATGGACGTGGTTATCAGCCTATGTT
GACGGAGATCAAAGCTGCTAATTTTAGTCAATCAGGAAAAATTATTAAATTAGACCTTACTTTCAAAGATGGTTTAGAGA
GGACTTTTGTTTATGCTTTTCATGAAAAAAATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (36-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	100	100	1
comYF	Streptococcus mutans UA159	99.306	100	0.993
comGF	Lactococcus lactis subsp. cremoris KW2	43.972	97.917	0.431
comGF/cglF	Streptococcus pneumoniae Rx1	40.299	93.056	0.375
comGF/cglF	Streptococcus pneumoniae D39	40.299	93.056	0.375
comGF/cglF	Streptococcus pneumoniae R6	40.299	93.056	0.375
comGF/cglF	Streptococcus pneumoniae TIGR4	40.299	93.056	0.375
comGF/cglF	Streptococcus mitis NCTC 12261	38.806	93.056	0.361