Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EL136_RS09405 Genome accession   NZ_LR134317
Coordinates   1963809..1965032 (-) Length   407 a.a.
NCBI ID   WP_012516520.1    Uniprot ID   A0AAW3GJZ4
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1958809..1970032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS09380 (NCTC6180_01923) - 1959275..1959637 (-) 363 WP_012678755.1 helix-turn-helix domain-containing protein -
  EL136_RS09385 (NCTC6180_01924) - 1959761..1959958 (-) 198 WP_012514683.1 DUF951 domain-containing protein -
  EL136_RS09390 (NCTC6180_01925) dnaN 1960036..1961172 (-) 1137 WP_154804260.1 DNA polymerase III subunit beta -
  EL136_RS09395 (NCTC6180_01926) dnaA 1961329..1962681 (-) 1353 WP_014622072.1 chromosomal replication initiator protein DnaA -
  EL136_RS09400 (NCTC6180_01927) spo0J 1962916..1963689 (-) 774 WP_012678752.1 ParB/RepB/Spo0J family partition protein Regulator
  EL136_RS09405 (NCTC6180_01928) htrA 1963809..1965032 (-) 1224 WP_012516520.1 S1C family serine protease Regulator
  EL136_RS09410 (NCTC6180_01929) rlmH 1965242..1965721 (+) 480 WP_154804261.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EL136_RS09430 (NCTC6180_01933) - 1966813..1969398 (-) 2586 WP_154804262.1 YfhO family protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42434.01 Da        Isoelectric Point: 5.4809

>NTDB_id=1121298 EL136_RS09405 WP_012516520.1 1963809..1965032(-) (htrA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGATTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAAS
PAISNPYINLFGEENDTSAVQKEDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVTSRNEAGETISTNAIQTDAAINP
GNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGIGFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQ
LNIPTSVTSGVVVASTQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKVDIKLTKTT
KDLTKKQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=1121298 EL136_RS09405 WP_012516520.1 1963809..1965032(-) (htrA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
GTGTTAAAATCAAAAAATATATTGAAGCCCTTATGGGTTTTAGCCATTGGATTTTTAGGGGGCTTATTAGCTGCCTTAGT
TGTTAATGGATTTAGTCAGAATTCTCTAACATCTTCAAATGCAAAGGGAGCAACGACAACAAGCAACGTCAGCTTTAATA
ATACAACTGATACAACAAAGGCTGTTAAGGTGGTTCAAGATGCTGTAGTGTCTGTTATTAACTATCAAAAGGCTGCTTCG
CCTGCCATTTCAAATCCTTACATCAATCTTTTCGGAGAAGAAAATGATACCTCAGCAGTACAAAAAGAGGACGAGCTAAG
CATACACAGTGAAGGCTCGGGTGTTGTCTACAAAAAAGAAGGAAATACTGCTTATCTTGTAACCAACAATCATGTTATTG
AGGGAGCTCAACGAATTGAAATTTTAACAGCAGACGGCTCTAAGATCGTTGGAGAACTAGTTGGTGCAGACACTTATTCT
GACCTAGCTGTTGTCAAAGTTGCTGCTGATAAAATCAAAACAATAGCCAAATTTGCAGATTCAACCAAAATTAATGTTGG
AGAGGTAGCCATTGCAATTGGTAGTCCTCTTGGAACAAAATATGCCAACTCAGTGACAGAAGGGATTGTTTCAAGTCTAA
GCCGTACAGTCACTTCAAGAAATGAGGCAGGCGAGACCATCTCAACAAATGCTATCCAAACTGATGCTGCTATCAATCCA
GGTAATTCAGGTGGACCACTCATCAATATTGAAGGCCAGGTTATTGGTATCAACTCAAGTAAAATATCCTCAACACCTAC
TGGTAGCGGCGGAGCCATTGAGGGAATTGGCTTTGCTATTCCATCAAGCGATGTTGTCACCATTATTAACCAACTAGAGT
CTAACGGAGCTGTTATCAGACCAGCCTTAGGCATTACAATGGTAAACTTAAGTAATCTATCAACCAATGCATTGATTCAA
TTGAATATTCCAACAAGCGTTACCAGCGGTGTTGTCGTAGCCTCTACTCAAGATGGCATGCCTGCTCTTGGTAAATTGGA
GCAGTATGATGTCATTACTGAGGTTGACGGTAAAGAAGTCAGCTCAATTAGTGACCTACAAAGTGTCTTATATAGTCATG
AGATTAACGACACCATTAAGGTAACCTTCTACAGAGGAACTGCTAAGAAGAAAGTTGACATCAAATTAACAAAAACAACT
AAGGATCTAACTAAAAAGCAGTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(112-257)

PDZ domain (PDZ_2)

(301-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.275

100

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

57.855

98.526

0.57
  htrA Streptococcus mitis NCTC 12261

54.66

97.543

0.533
  htrA Streptococcus pneumoniae Rx1

53.634

98.034

0.526
  htrA Streptococcus pneumoniae D39

53.634

98.034

0.526
  htrA Streptococcus pneumoniae R6

53.634

98.034

0.526
  htrA Streptococcus pneumoniae TIGR4

53.634

98.034

0.526

Multiple sequence alignment