Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   EL136_RS01610 Genome accession   NZ_LR134317
Coordinates   327621..328331 (+) Length   236 a.a.
NCBI ID   WP_154803663.1    Uniprot ID   A0A7Z9D241
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 322621..333331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS01590 (NCTC6180_00326) - 323448..323987 (+) 540 WP_154803661.1 hypothetical protein -
  EL136_RS01595 (NCTC6180_00327) - 323984..325099 (+) 1116 WP_154803662.1 acetyl-CoA C-acyltransferase -
  EL136_RS01600 (NCTC6180_00328) - 325089..326351 (+) 1263 WP_043040863.1 AMP-binding protein -
  EL136_RS01605 (NCTC6180_00329) - 326396..327412 (+) 1017 WP_012677634.1 DUF3114 domain-containing protein -
  EL136_RS01610 (NCTC6180_00330) vicR 327621..328331 (+) 711 WP_154803663.1 response regulator YycF Regulator
  EL136_RS01615 (NCTC6180_00331) vicK 328324..329676 (+) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL136_RS01620 (NCTC6180_00332) vicX 329680..330489 (+) 810 WP_043052256.1 MBL fold metallo-hydrolase Regulator
  EL136_RS01625 (NCTC6180_00333) - 331401..332915 (+) 1515 WP_043039170.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26951.81 Da        Isoelectric Point: 4.9038

>NTDB_id=1121261 EL136_RS01610 WP_154803663.1 327621..328331(+) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MKKILIVDDEKPISDIIKFNLTKEGYDAVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1121261 EL136_RS01610 WP_154803663.1 327621..328331(+) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TGCGGTCACAGCCTTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAGCTAGATGGTCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGCCTTGAAATAGGGGCCGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATTGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Z9D241

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.559

100

0.886
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377

Multiple sequence alignment