Detailed information NTG1121118

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL107_RS02080
• Genome accession: NZ_LR134314
• Coordinates: 432069..432905 (-)
• Length: 278 a.a.
• NCBI ID: WP_011184519.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8302
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 427069..437905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL107_RS02070 (NCTC8302_00416)	trmFO	428352..429698 (-)	1347	WP_021340038.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
EL107_RS02075 (NCTC8302_00417)	topA	429833..431962 (-)	2130	WP_011184520.1	type I DNA topoisomerase	-
EL107_RS02080 (NCTC8302_00418)	dprA	432069..432905 (-)	837	WP_011184519.1	DNA-processing protein DprA	Machinery gene
EL107_RS02085 (NCTC8302_00419)	-	432970..433761 (-)	792	WP_126409733.1	ribonuclease HII	-
EL107_RS02090 (NCTC8302_00420)	ylqF	433751..434599 (-)	849	WP_011184517.1	ribosome biogenesis GTPase YlqF	-
EL107_RS02095 (NCTC8302_00421)	-	434818..435258 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
EL107_RS02100 (NCTC8302_00422)	trhA	435255..435905 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
EL107_RS02105 (NCTC8302_00423)	-	436022..436933 (+)	912	WP_011184516.1	diacylglycerol/lipid kinase family protein	-
EL107_RS02110 (NCTC8302_00424)	-	436983..437417 (-)	435	WP_011017767.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31136.17 Da
• Isoelectric Point: 9.2335

>NTDB_id=1121118 EL107_RS02080 WP_011184519.1 432069..432905(-) (dprA) [Streptococcus pyogenes strain NCTC8302]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMYILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1121118 EL107_RS02080 WP_011184519.1 432069..432905(-) (dprA) [Streptococcus pyogenes strain NCTC8302]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCTATTGTTGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGTATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363