Detailed information NTG1120570

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: EL096_RS07555
• Genome accession: NZ_LR134294
• Coordinates: 1401572..1401874 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NCTC12977
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1396572..1406874

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL096_RS07525 (NCTC12977_01465)	rnpA	1397251..1397622 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EL096_RS12050	-	1397639..1397770 (-)	132	WP_000768904.1	hypothetical protein	-
EL096_RS07530 (NCTC12977_01466)	-	1397771..1398961 (-)	1191	WP_000167766.1	acetate kinase	-
EL096_RS07535 (NCTC12977_01467)	comYH	1399012..1399965 (-)	954	WP_050308921.1	class I SAM-dependent methyltransferase	Machinery gene
EL096_RS07540	-	1400026..1400620 (-)	595	Protein_1404	class I SAM-dependent methyltransferase	-
EL096_RS07545 (NCTC12977_01470)	comGG/cglG	1400757..1401170 (-)	414	WP_050102600.1	competence type IV pilus minor pilin ComGG	Machinery gene
EL096_RS07550 (NCTC12977_01471)	comGF/cglF	1401148..1401609 (-)	462	WP_000250544.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL096_RS07555 (NCTC12977_01472)	comGE/cglE	1401572..1401874 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL096_RS07560 (NCTC12977_01473)	comGD/cglD	1401837..1402241 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL096_RS07565 (NCTC12977_01474)	comGC/cglC	1402234..1402560 (-)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
EL096_RS07570 (NCTC12977_01475)	comGB/cglB	1402562..1403578 (-)	1017	WP_114880773.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL096_RS07575 (NCTC12977_01476)	comGA/cglA/cilD	1403526..1404467 (-)	942	WP_000249549.1	competence type IV pilus ATPase ComGA	Machinery gene
EL096_RS07580 (NCTC12977_01477)	-	1404543..1404908 (-)	366	WP_000286415.1	DUF1033 family protein	-
EL096_RS07585 (NCTC12977_01478)	-	1405059..1406117 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=1120570 EL096_RS07555 WP_000413380.1 1401572..1401874(-) (comGE/cglE) [Streptococcus pneumoniae strain NCTC12977]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1120570 EL096_RS07555 WP_000413380.1 1401572..1401874(-) (comGE/cglE) [Streptococcus pneumoniae strain NCTC12977]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39