Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EL096_RS07535 Genome accession   NZ_LR134294
Coordinates   1399012..1399965 (-) Length   317 a.a.
NCBI ID   WP_050308921.1    Uniprot ID   A0A4J2CWK8
Organism   Streptococcus pneumoniae strain NCTC12977     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1394012..1404965
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL096_RS07510 (NCTC12977_01462) - 1394773..1395396 (-) 624 WP_114880772.1 ribonuclease P -
  EL096_RS07515 (NCTC12977_01463) jag 1395447..1396433 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  EL096_RS07520 (NCTC12977_01464) - 1396452..1397276 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  EL096_RS07525 (NCTC12977_01465) rnpA 1397251..1397622 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EL096_RS12050 - 1397639..1397770 (-) 132 WP_000768904.1 hypothetical protein -
  EL096_RS07530 (NCTC12977_01466) - 1397771..1398961 (-) 1191 WP_000167766.1 acetate kinase -
  EL096_RS07535 (NCTC12977_01467) comYH 1399012..1399965 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  EL096_RS07540 - 1400026..1400620 (-) 595 Protein_1404 class I SAM-dependent methyltransferase -
  EL096_RS07545 (NCTC12977_01470) comGG/cglG 1400757..1401170 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL096_RS07550 (NCTC12977_01471) comGF/cglF 1401148..1401609 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL096_RS07555 (NCTC12977_01472) comGE/cglE 1401572..1401874 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL096_RS07560 (NCTC12977_01473) comGD/cglD 1401837..1402241 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL096_RS07565 (NCTC12977_01474) comGC/cglC 1402234..1402560 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  EL096_RS07570 (NCTC12977_01475) comGB/cglB 1402562..1403578 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL096_RS07575 (NCTC12977_01476) comGA/cglA/cilD 1403526..1404467 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  EL096_RS07580 (NCTC12977_01477) - 1404543..1404908 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35776.95 Da        Isoelectric Point: 4.2434

>NTDB_id=1120567 EL096_RS07535 WP_050308921.1 1399012..1399965(-) (comYH) [Streptococcus pneumoniae strain NCTC12977]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDTIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1120567 EL096_RS07535 WP_050308921.1 1399012..1399965(-) (comYH) [Streptococcus pneumoniae strain NCTC12977]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATACCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J2CWK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment