Detailed information NTG1120452

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EL084_RS06895
• Genome accession: NZ_LR134292
• Coordinates: 1385645..1386547 (+)
• Length: 300 a.a.
• NCBI ID: WP_126440601.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC10389
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1380645..1391547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL084_RS06870	-	1381842..1382291 (+)	450	Protein_1322	DUF523 domain-containing protein	-
EL084_RS06875 (NCTC10389_01458)	purE	1382291..1382779 (+)	489	WP_003067257.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
EL084_RS06880 (NCTC10389_01459)	purK	1382766..1383857 (+)	1092	WP_126440599.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EL084_RS06885 (NCTC10389_01460)	-	1383877..1384101 (+)	225	WP_126440600.1	phosphoribosylaminoimidazole carboxylase	-
EL084_RS06890 (NCTC10389_01461)	purB	1384191..1385489 (+)	1299	WP_003067249.1	adenylosuccinate lyase	-
EL084_RS06895 (NCTC10389_01462)	comR	1385645..1386547 (+)	903	WP_126440601.1	helix-turn-helix domain-containing protein	Regulator
EL084_RS06900 (NCTC10389_01463)	ruvB	1386720..1387718 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
EL084_RS06905 (NCTC10389_01464)	-	1387928..1388359 (+)	432	WP_126440602.1	low molecular weight protein-tyrosine-phosphatase	-
EL084_RS06910 (NCTC10389_01465)	-	1388376..1388756 (+)	381	WP_074451189.1	MORN repeat-containing protein	-
EL084_RS06915 (NCTC10389_01466)	-	1388753..1390546 (+)	1794	WP_126440603.1	acyltransferase family protein	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35325.30 Da
• Isoelectric Point: 4.9461

>NTDB_id=1120452 EL084_RS06895 WP_126440601.1 1385645..1386547(+) (comR) [Streptococcus equinus strain NCTC10389]
MKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKELKY
LLLRTPTYGDQERVDRKNDYFDEISENYYDIIPEEEKLIIDCLQSKFDVHFSDDVNFGDGILNDYFDQVIRKETFNINDL
ILIDLYCVCMASAKAYTGIYSLDIYDNLMDCLLNQSHVTPETSLILNNVLLNNIALAFQFEREDYVYKVIKISDRIMTEI
HDFQRRPILSLVEWKYYLKFKHDYDSAKQSFTHATLFARLIGDVYLENKLKEEWKFDTTT

Nucleotide

• Length: 903 bp

>NTDB_id=1120452 EL084_RS06895 WP_126440601.1 1385645..1386547(+) (comR) [Streptococcus equinus strain NCTC10389]
GTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGACGAGAC
CGAATTATCCGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCACAATTCATTGCTA
ATCGCCTTGGTGTAAAACTCGGAACCCTGACAGACGGCGATAGCTTAGAATTACCAAAGCGGTATAAAGAGCTGAAGTAT
TTGTTGCTTAGGACACCGACGTATGGCGATCAAGAGAGAGTTGATCGGAAAAATGATTATTTTGATGAGATATCAGAAAA
TTATTATGATATTATTCCTGAAGAAGAGAAACTCATCATAGATTGTTTACAGTCAAAATTTGATGTTCATTTTAGTGATG
ACGTAAATTTTGGTGATGGTATTTTAAATGATTATTTTGATCAAGTTATTCGTAAAGAGACTTTTAATATCAATGATTTA
ATTTTGATTGATCTTTACTGTGTATGCATGGCATCTGCTAAAGCGTATACTGGAATTTACAGTTTGGATATTTACGATAA
TTTGATGGATTGCTTATTAAATCAAAGTCATGTTACGCCGGAGACTAGTTTGATTTTAAATAATGTGTTGTTAAATAATA
TTGCTCTGGCTTTTCAATTTGAACGAGAAGACTACGTTTATAAAGTGATTAAGATAAGCGATAGGATTATGACTGAGATT
CATGATTTTCAACGTCGCCCAATTTTAAGCTTAGTTGAATGGAAATATTATTTGAAGTTTAAACATGATTATGACAGTGC
AAAACAATCTTTTACACACGCAACTTTATTTGCAAGATTAATCGGTGATGTTTACCTAGAAAACAAACTTAAAGAAGAAT
GGAAATTCGATACAACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-61)

• ComR tetratricopeptide (ComR_TPR) (72-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	81.882	95.667	0.783
comR	Streptococcus mutans UA159	52.508	99.667	0.523
comR	Streptococcus pyogenes MGAS8232	50	100	0.503
comR	Streptococcus pyogenes MGAS315	44.631	99.333	0.443
comR	Streptococcus suis D9	38.333	100	0.383
comR	Streptococcus suis P1/7	38.384	99	0.38
comR	Streptococcus suis 05ZYH33	38.384	99	0.38