Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EL092_RS03930 Genome accession   NZ_LR134291
Coordinates   818655..819356 (+) Length   233 a.a.
NCBI ID   WP_012000241.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7868     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 813655..824356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL092_RS03905 (NCTC7868_00774) - 813998..815311 (+) 1314 WP_012000237.1 glycosyltransferase family 4 protein -
  EL092_RS03910 (NCTC7868_00775) - 815347..815709 (+) 363 WP_012000238.1 hypothetical protein -
  EL092_RS10830 (NCTC7868_00777) - 816043..816414 (+) 372 WP_012000239.1 hypothetical protein -
  EL092_RS03925 (NCTC7868_00778) thrS 816506..818449 (+) 1944 WP_012000240.1 threonine--tRNA ligase -
  EL092_RS03930 (NCTC7868_00779) micA 818655..819356 (+) 702 WP_012000241.1 response regulator YycF Regulator
  EL092_RS03935 (NCTC7868_00780) micB 819349..820710 (+) 1362 WP_008809003.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL092_RS03940 (NCTC7868_00781) vicX 820703..821506 (+) 804 WP_008809002.1 MBL fold metallo-hydrolase Regulator
  EL092_RS03945 (NCTC7868_00782) - 821541..821897 (+) 357 WP_008809001.1 YbaN family protein -
  EL092_RS03950 (NCTC7868_00783) rnc 822140..822838 (+) 699 WP_012000242.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26817.56 Da        Isoelectric Point: 4.6297

>NTDB_id=1120356 EL092_RS03930 WP_012000241.1 818655..819356(+) (micA) [Streptococcus gordonii strain NCTC7868]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQENEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1120356 EL092_RS03930 WP_012000241.1 818655..819356(+) (micA) [Streptococcus gordonii strain NCTC7868]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTCTTGAGATGTTTGAAGCTGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTTGAGATCGGAGCAGACGACTATGTGACTAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAATGAAAAGGGCTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCCGATGCTTTTGTTGCCAAAAAACATGGTGAAGAGCTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCTAGTCATGTTGGTCAAGTAATGACACGCGAACACCTGTTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGTCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTACTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

80

100

0.807
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

99.142

0.446
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373

Multiple sequence alignment