Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EL092_RS03025 Genome accession   NZ_LR134291
Coordinates   650133..651986 (+) Length   617 a.a.
NCBI ID   WP_012000094.1    Uniprot ID   A8AVV6
Organism   Streptococcus gordonii strain NCTC7868     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 645133..656986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL092_RS03010 (NCTC7868_00596) fmt 647137..648072 (+) 936 WP_012000091.1 methionyl-tRNA formyltransferase -
  EL092_RS03015 (NCTC7868_00597) rsmB 648062..649375 (+) 1314 WP_012000092.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL092_RS03020 (NCTC7868_00598) - 649396..650136 (+) 741 WP_012000093.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL092_RS03025 (NCTC7868_00599) stkP 650133..651986 (+) 1854 WP_012000094.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL092_RS03030 (NCTC7868_00600) liaF 652160..652858 (+) 699 WP_012000095.1 cell wall-active antibiotics response protein LiaF -
  EL092_RS03035 (NCTC7868_00601) - 652855..653856 (+) 1002 WP_041789569.1 sensor histidine kinase -
  EL092_RS03040 (NCTC7868_00602) - 653858..654490 (+) 633 WP_041789571.1 response regulator transcription factor -
  EL092_RS03045 (NCTC7868_00603) - 654578..655981 (+) 1404 WP_012000098.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL092_RS03050 (NCTC7868_00604) - 655978..656364 (+) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67153.19 Da        Isoelectric Point: 6.5204

>NTDB_id=1120346 EL092_RS03025 WP_012000094.1 650133..651986(+) (stkP) [Streptococcus gordonii strain NCTC7868]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLSMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHARGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENANVP
QSLENVIIKATAKKLTDRYQSVSDMYVDLSSCLSPERRNEKKLMFDDAVKVDTKTLPKIPQVTPPVASRVNNDPATDVEQ
KAPQVAPPTKPKTKRHLRARYKVLLAAVFLVIAAFLALLYLTPSNKQVPDVTGKTVAEAREAIEKVNLKVGEEIEENSDE
VASGMIIRTDPVAGTQRKEGSTVNLVVSKGAKTLIMEDYTGQTTAQAVERLTDVLKVPKNNIKVEEVETNDVEEGTIFEQ
TPAAGATYDLTSNTKIVLKVAKAVSTIEMPNFGSLQYTYANARNYLISLGIPSSNIERVVDRSVVSSQSDLVTSQSPATG
PVNPKKVKVTLYVTEATTQSSSSSSSSNSNSSSSSKNTTSSSSSEDETSASSSTHGD

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=1120346 EL092_RS03025 WP_012000094.1 650133..651986(+) (stkP) [Streptococcus gordonii strain NCTC7868]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCAAACAAATTGGCCGAGGCGGGATGGCAGATGTCTA
TCTTGCCAAGGATTTGATTTTAGATGGTGAAGAAGTGGCGGTTAAGGTTCTTAGAACCAATTACCAGACGGATCCTATCG
CTGTTGCACGTTTCCAACGAGAAGCGCGTGCCATGGCGGATTTGGATCATCCACATATCGTTCGCATCACCGACATTGGT
GAAGAAGATGGCCAGCAATATTTGTCTATGGAATATGTAGCTGGCTTGGATCTCAAACGATACATTAAAGAGCACGCTCC
TTTGTCGAACGAGGAGGCCGTTCGAATTATGGGGCAAATTCTTTTAGCCATGCGTTTGGCACATGCTCGTGGGATTGTTC
ACCGAGATTTGAAACCGCAAAACGTTCTCCTGACACCTGATGGAAATGCCAAGGTAACGGACTTTGGGATTGCGGTTGCC
TTTGCAGAAACAAGTTTGACCCAAACAAATTCCATGCTTGGCAGTGTCCATTATTTGTCTCCTGAGCAGGCGCGTGGTTC
GAAAGCAACTTTCCAAAGTGATATTTATGCGATGGGTATCATCTTTTATGAGATGCTGACTGGTCATATTCCTTATGATG
GGGATAGTGCAGTGACTATCGCTCTGCAACATTTCCAAAAACCATTGCCGTCCATTATTGCTGAAAACGCTAATGTTCCG
CAGTCTTTGGAAAATGTTATTATTAAGGCGACTGCTAAAAAGCTGACAGACCGATATCAGAGTGTTTCGGATATGTATGT
AGATCTGTCTAGTTGCCTGTCACCTGAAAGACGGAATGAAAAGAAACTGATGTTTGATGACGCGGTAAAAGTGGATACTA
AAACACTTCCAAAGATTCCGCAAGTTACACCTCCTGTAGCTTCTAGAGTAAATAATGATCCAGCTACAGATGTTGAACAG
AAAGCTCCTCAAGTTGCACCGCCAACGAAACCTAAGACAAAGCGTCATTTGAGAGCGAGATACAAGGTTTTGTTAGCTGC
AGTATTTCTGGTCATTGCTGCTTTTCTGGCTTTGCTCTATCTAACACCATCTAATAAGCAGGTTCCAGATGTTACTGGCA
AGACCGTTGCTGAAGCTAGAGAAGCGATTGAAAAAGTCAATTTAAAAGTTGGTGAAGAGATAGAAGAGAATAGTGATGAA
GTAGCTTCTGGAATGATTATTCGAACAGATCCAGTGGCAGGGACTCAGAGAAAAGAAGGCAGTACAGTTAACTTAGTTGT
TTCTAAGGGAGCTAAAACGCTGATCATGGAAGACTATACAGGTCAAACTACTGCTCAAGCTGTTGAGAGACTCACTGATG
TTCTAAAAGTTCCAAAAAACAATATTAAAGTTGAAGAAGTTGAAACAAACGATGTAGAAGAAGGAACAATTTTTGAACAG
ACACCAGCTGCGGGAGCTACCTATGATCTCACTTCAAATACGAAGATTGTTTTAAAAGTAGCCAAAGCAGTATCAACGAT
TGAAATGCCAAACTTTGGTAGCCTTCAATATACTTATGCAAACGCTCGAAATTATCTAATATCTCTAGGAATTCCATCTA
GTAACATTGAAAGAGTCGTGGATCGTTCAGTTGTGTCGAGTCAATCTGATTTAGTGACATCACAATCTCCAGCAACTGGA
CCAGTTAATCCTAAGAAGGTAAAAGTAACCTTATATGTAACTGAAGCAACTACTCAAAGTTCAAGTTCTAGCTCAAGTTC
GAATTCTAACTCCTCATCAAGTAGCAAGAATACGACATCGTCAAGTTCTTCAGAAGATGAAACTTCAGCATCAAGTTCGA
CACATGGTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(435-502)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(508-574)

Protein kinase domain (Pkinase)

(12-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AVV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

70.192

84.279

0.592
  stkP Streptococcus pneumoniae D39

70

84.279

0.59
  stkP Streptococcus pneumoniae R6

70

84.279

0.59
  stkP Streptococcus pneumoniae Rx1

69.808

84.279

0.588
  pknB Streptococcus mutans UA159

57.941

92.869

0.538
  stkP/pknB Streptococcus salivarius strain HSISS4

57.847

88.817

0.514

Multiple sequence alignment