Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   EL100_RS03910 Genome accession   NZ_LR134285
Coordinates   744636..746789 (+) Length   717 a.a.
NCBI ID   WP_126404999.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 739636..751789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS03890 (NCTC3168_00804) rplI 741039..741491 (+) 453 WP_126405000.1 50S ribosomal protein L9 -
  EL100_RS03895 (NCTC3168_00805) dnaB 741516..742871 (+) 1356 WP_006596978.1 replicative DNA helicase -
  EL100_RS03900 (NCTC3168_00806) - 742875..743147 (+) 273 WP_006595358.1 Veg family protein -
  EL100_RS03905 (NCTC3168_00807) rpsD 743742..744353 (+) 612 WP_003009175.1 30S ribosomal protein S4 -
  EL100_RS03910 (NCTC3168_00808) comA 744636..746789 (+) 2154 WP_126404999.1 peptide cleavage/export ABC transporter ComA Regulator
  EL100_RS03915 (NCTC3168_00809) comB 746817..748178 (+) 1362 WP_126404998.1 bacteriocin secretion accessory protein Regulator
  EL100_RS03920 (NCTC3168_00810) - 748490..749026 (-) 537 WP_126404997.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80831.34 Da        Isoelectric Point: 7.8655

>NTDB_id=1120172 EL100_RS03910 WP_126404999.1 744636..746789(+) (comA) [Streptococcus australis strain NCTC3168]
MGFKKKHYRQQVDMRDCGVAALAMVFGYYGSYYSLASLREKAKTTADGTTALGLVKVAEELGFETRAFRADRTLFDLEGV
TYPLIVHVIKDGRLPHYYVVYKKDKKHLYIADPDPNVKMTKLTIEEFEKEWTGIVIALAPTPAYQPSKEKKNGLLDFVPL
LFKQRQLVLHIVLATLLVTLINIVGSYYLQSIIDTYVPDQMKQTLSVISLGLIVVYILQQVLTYAQDYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEVVSRFTDANRIIDALASTLLSIFLDLSIVLILSVVLFSQNAHLFFLTILLLPIYAV
IIFAFMKPFERLNNETMEANSVLSSSIIEDINGIETIKSLTSERSRYQKIDTEFVDYLKKSFAMSKAESLQKGLKHLAQL
ILNVLVLWMGAHLVMKQELSLGQLITYNTLLVYFTGPLENLINLQTKLQAARVANTRLNEVYLIDSEFAEKKPLQERETL
DGDLVFEGVDYKYGFGANVITDINLKIKKGSKVSFVGISGSGKTTLAKMMVNFYKPNKGTIRLGGTDIQQVDKTLLRQQI
NYLPQQPYVFNGTILENLLLGAREGTSQEDILRAVEIAGIREDIERMPLNYQTELTTDGMGISGGQRQRIALARALLTDA
PILILDEATSSLDILTEKKIVDSLMALDKTIIFIAHRLTIAERSEKVFLLDQGCLKEEGSHEELLKKNGYYSHLVTC

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1120172 EL100_RS03910 WP_126404999.1 744636..746789(+) (comA) [Streptococcus australis strain NCTC3168]
ATGGGATTTAAGAAAAAACATTATCGCCAACAAGTTGACATGAGAGATTGCGGTGTTGCAGCTTTAGCCATGGTCTTTGG
TTACTATGGATCATACTATTCTTTAGCTAGTCTGAGGGAGAAGGCAAAAACGACTGCAGATGGAACGACCGCCTTAGGTC
TGGTCAAGGTGGCTGAGGAGTTGGGATTTGAGACACGCGCCTTCCGAGCAGACCGCACACTTTTTGACTTGGAAGGAGTG
ACCTATCCATTGATTGTCCACGTGATTAAGGATGGGCGTCTCCCTCACTATTACGTAGTCTATAAGAAAGATAAAAAGCA
TCTTTACATAGCAGATCCAGATCCAAATGTAAAGATGACCAAATTGACGATCGAAGAGTTTGAAAAGGAATGGACAGGGA
TTGTCATTGCCCTGGCCCCGACTCCAGCCTATCAACCGAGTAAAGAAAAGAAAAATGGGCTCCTAGACTTTGTCCCTCTT
TTGTTTAAACAGCGACAATTAGTCCTTCATATTGTTCTTGCAACGTTATTGGTAACCCTTATCAATATTGTTGGTTCTTA
CTACCTACAATCGATTATTGATACCTATGTGCCTGATCAGATGAAGCAGACCCTAAGTGTGATTTCACTAGGTTTGATCG
TGGTTTACATCTTACAGCAGGTTCTGACCTATGCGCAAGATTACTTGCTTCTTGTTTTAGGTCAACGTTTGTCTATTGAT
GTCATACTGTCCTATATTAAGCATGTTTTTCAGTTGCCTATGAGTTTCTTTGCAACTCGACGGACAGGAGAAGTGGTGTC
GCGGTTTACAGATGCCAACCGGATTATCGATGCTCTGGCTAGTACGCTACTTTCAATCTTTTTGGATCTGTCCATAGTCC
TGATTTTATCAGTGGTCCTGTTTAGCCAAAATGCTCATCTCTTTTTCTTGACCATTCTCTTACTGCCGATTTATGCAGTC
ATTATTTTTGCCTTTATGAAGCCTTTTGAGCGCTTAAATAATGAAACAATGGAAGCCAATAGTGTCTTGTCTTCTTCTAT
TATCGAAGATATCAATGGGATTGAAACCATCAAGTCTCTTACCAGTGAGCGTAGTCGTTATCAAAAGATTGACACAGAAT
TTGTGGACTATCTCAAGAAGTCCTTTGCCATGAGCAAGGCGGAGAGTCTGCAAAAGGGGCTCAAGCACTTGGCCCAATTG
ATTTTGAATGTCTTGGTCTTGTGGATGGGGGCTCATTTGGTCATGAAGCAAGAATTGAGTTTGGGTCAGCTGATTACCTA
CAATACTCTCCTTGTTTATTTCACAGGGCCTCTAGAGAACTTGATCAACCTCCAAACAAAACTTCAAGCAGCCCGAGTGG
CCAATACCCGTCTGAATGAAGTCTATTTGATAGACTCTGAGTTCGCAGAGAAGAAGCCTCTTCAAGAGCGTGAGACTCTC
GATGGTGATCTGGTTTTTGAGGGAGTAGACTACAAGTACGGTTTTGGAGCCAATGTTATAACAGATATTAACTTAAAGAT
CAAAAAAGGGAGCAAGGTAAGTTTTGTCGGTATTTCCGGTTCTGGAAAAACCACGCTAGCGAAGATGATGGTGAATTTCT
ACAAACCCAATAAAGGGACGATTCGGCTGGGAGGGACGGATATCCAGCAAGTGGATAAGACCTTGCTCCGCCAGCAAATC
AATTATTTACCCCAGCAGCCCTATGTCTTTAATGGTACGATTTTAGAGAACTTGTTACTGGGAGCGCGGGAAGGAACCAG
TCAGGAAGATATTTTGCGCGCTGTTGAAATAGCAGGAATTCGAGAAGACATTGAGCGCATGCCCCTCAATTACCAAACGG
AATTGACTACGGATGGCATGGGAATTTCTGGTGGACAACGGCAGCGGATTGCCTTGGCGCGTGCCTTATTAACGGATGCT
CCGATTCTGATTCTGGATGAAGCGACCAGTAGCCTGGATATTTTGACGGAGAAGAAAATTGTGGACAGCTTGATGGCCTT
AGATAAAACCATTATCTTTATTGCCCACCGGTTAACGATTGCAGAGCGTTCTGAAAAAGTCTTCCTCCTGGACCAAGGTT
GTCTTAAGGAGGAAGGAAGTCATGAAGAACTGCTGAAAAAGAATGGCTATTACAGTCATTTGGTTACTTGTTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(171-438)

ABC transporter (ABC_tran)

(501-650)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

76.987

100

0.77
  comA Streptococcus mitis NCTC 12261

75.174

100

0.752
  comA Streptococcus pneumoniae Rx1

75.035

100

0.75
  comA Streptococcus pneumoniae D39

75.035

100

0.75
  comA Streptococcus pneumoniae R6

75.035

100

0.75
  comA Streptococcus mitis SK321

75.035

100

0.75
  comA Streptococcus pneumoniae TIGR4

74.616

100

0.746
  comA/nlmT Streptococcus mutans UA159

63.357

99.721

0.632

Multiple sequence alignment