Detailed information NTG1119977

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL078_RS04770
• Genome accession: NZ_LR134282
• Coordinates: 927319..928161 (-)
• Length: 280 a.a.
• NCBI ID: WP_045797921.1
• Uniprot ID: A0A239RAI3
• Organism: Streptococcus equinus strain NCTC8140
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 922319..933161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL078_RS04755 (NCTC8140_00959)	-	923448..924170 (-)	723	WP_126437842.1	DUF3307 domain-containing protein	-
EL078_RS04760 (NCTC8140_00960)	-	924170..924835 (-)	666	WP_126437843.1	SatD family protein	-
EL078_RS04765 (NCTC8140_00961)	topA	924976..927114 (-)	2139	WP_024344084.1	type I DNA topoisomerase	-
EL078_RS04770 (NCTC8140_00962)	dprA	927319..928161 (-)	843	WP_045797921.1	DNA-processing protein DprA	Machinery gene
EL078_RS04775 (NCTC8140_00963)	-	928232..928783 (-)	552	WP_024344082.1	sugar O-acetyltransferase	-
EL078_RS04780 (NCTC8140_00964)	-	928783..929562 (-)	780	WP_126437844.1	ribonuclease HII	-
EL078_RS04785 (NCTC8140_00965)	ylqF	929549..930403 (-)	855	WP_033152632.1	ribosome biogenesis GTPase YlqF	-
EL078_RS04790 (NCTC8140_00966)	-	930625..931014 (+)	390	WP_126437845.1	DUF4231 domain-containing protein	-
EL078_RS04795 (NCTC8140_00967)	-	931219..931542 (-)	324	WP_039698237.1	hypothetical protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 30819.74 Da
• Isoelectric Point: 8.6675

>NTDB_id=1119977 EL078_RS04770 WP_045797921.1 927319..928161(-) (dprA) [Streptococcus equinus strain NCTC8140]
MNNFELFKLKQAGLTNLNILALLDYQSKQEKSLSLRDMAVASKCKNPILFMEKYKSLDSKSLRKVFNQYPSISILDDEYP
IELKNCYNPPVLLFYQGNVDLLKRPKMAVVGARTASQTGTKSVQKIVSELGNQFVIVSGLARGIDTSAHISALKNGGATI
AVIGCGLDVHYPKENKLLQEYLGKNHLILSEYAVGEAPLKFHFPERNRIIAGLSQGVIVAEAKMRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCITSGMDVLSEYQL

Nucleotide

• Length: 843 bp

>NTDB_id=1119977 EL078_RS04770 WP_045797921.1 927319..928161(-) (dprA) [Streptococcus equinus strain NCTC8140]
ATGAACAATTTTGAATTATTTAAATTAAAACAAGCAGGACTAACTAATCTTAATATTTTGGCTCTTTTGGATTATCAGAG
TAAACAAGAAAAATCTTTGTCCTTGCGAGATATGGCTGTAGCTTCAAAGTGTAAGAATCCGATTCTTTTCATGGAAAAAT
ACAAATCTCTTGATAGTAAATCATTACGCAAAGTTTTCAATCAGTATCCTAGTATTTCAATACTAGACGATGAATATCCA
ATAGAATTGAAGAATTGCTATAATCCGCCTGTTTTGCTCTTTTACCAAGGCAACGTAGATTTGCTTAAACGTCCAAAAAT
GGCAGTAGTAGGAGCGAGGACAGCCTCTCAAACAGGAACAAAATCTGTTCAAAAGATTGTTAGTGAACTCGGAAATCAGT
TTGTTATTGTTAGCGGGTTGGCGCGTGGAATTGACACAAGTGCACACATTTCAGCGTTAAAAAATGGCGGAGCGACTATA
GCCGTTATCGGCTGTGGTTTAGACGTTCATTACCCTAAAGAAAACAAGTTATTGCAAGAATATCTAGGTAAAAATCACCT
AATTCTAAGTGAGTACGCAGTAGGAGAAGCTCCACTAAAATTCCATTTTCCAGAACGCAATCGCATCATTGCGGGATTGT
CTCAAGGTGTTATTGTAGCAGAAGCAAAAATGCGTTCAGGTAGTTTAATTACTTGCGAGAGAGCACTGGAAGAAGGACGA
GATGTTTTTGCAATTCCAGGAAATATCTTGGATGGAAAATCCGACGGTTGCCATCACCTGATAAAGGAAGGAGCAAAATG
CATTACATCAGGCATGGATGTCCTCTCAGAATACCAATTATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A239RAI3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	73.214	100	0.732
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	64.643	100	0.646
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	64.643	100	0.646
dprA/cilB/dalA	Streptococcus pneumoniae D39	64.643	100	0.646
dprA/cilB/dalA	Streptococcus pneumoniae R6	64.643	100	0.646
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	64.643	100	0.646
dprA/cilB/dalA	Streptococcus mitis SK321	64.643	100	0.646
dprA	Lactococcus lactis subsp. cremoris KW2	61.151	99.286	0.607
dprA	Bacillus subtilis subsp. subtilis str. 168	40.892	96.071	0.393
dprA	Latilactobacillus sakei subsp. sakei 23K	40.613	93.214	0.379