Detailed information NTG1119946

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EL078_RS00350
• Genome accession: NZ_LR134282
• Coordinates: 50990..51901 (+)
• Length: 303 a.a.
• NCBI ID: WP_039691866.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC8140
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45990..56901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL078_RS00325 (NCTC8140_00064)	-	47190..47639 (+)	450	WP_126437520.1	DUF523 domain-containing protein	-
EL078_RS00330 (NCTC8140_00065)	purE	47639..48127 (+)	489	WP_021141395.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
EL078_RS00335 (NCTC8140_00066)	purK	48114..49205 (+)	1092	WP_126437521.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EL078_RS00340 (NCTC8140_00067)	-	49227..49451 (+)	225	WP_027968247.1	hypothetical protein	-
EL078_RS00345 (NCTC8140_00068)	purB	49542..50840 (+)	1299	WP_024344772.1	adenylosuccinate lyase	-
EL078_RS00350 (NCTC8140_00069)	comR	50990..51901 (+)	912	WP_039691866.1	helix-turn-helix domain-containing protein	Regulator
EL078_RS00355 (NCTC8140_00070)	ruvB	52072..53070 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
EL078_RS00360 (NCTC8140_00071)	-	53280..53711 (+)	432	WP_126437522.1	low molecular weight protein-tyrosine-phosphatase	-
EL078_RS00365 (NCTC8140_00072)	-	53728..54108 (+)	381	WP_021141401.1	MORN repeat-containing protein	-
EL078_RS00370 (NCTC8140_00073)	-	54105..55898 (+)	1794	WP_126437523.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35514.77 Da
• Isoelectric Point: 4.7033

>NTDB_id=1119946 EL078_RS00350 WP_039691866.1 50990..51901(+) (comR) [Streptococcus equinus strain NCTC8140]
MEVKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKEL
KYLILRTPTYKDEKRVNLRDSYFDEIYSDFYDDLPEEEQLIVECMRSKADVFLTDNSNLATKLLEDYFYQTKSKSHYSIN
DLIIIDLYMVCANASNYEYFMFDKDEFIGIAKNLLEQENHFSLAEIFVLNNILFGSLSLLVDLKMWDEVELTLDVLKGIM
AKIQDFHKKPVLNMIEWKYILERFGQTEKAQKLYEEAVLYANLIGDAYLANKITEEWIKDTTT

Nucleotide

• Length: 912 bp

>NTDB_id=1119946 EL078_RS00350 WP_039691866.1 50990..51901(+) (comR) [Streptococcus equinus strain NCTC8140]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGA
CGAGACCGAATTATCTGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCCCAATTCA
TTGCTAATCGCCTTGGCGTAAAACTTGGAACCCTGACAGACGGCGATAGCTTAGAATTACCAAAGCGGTATAAAGAGCTG
AAGTATTTAATTTTGCGTACACCAACGTATAAAGATGAAAAGCGTGTGAATTTAAGAGATTCTTATTTTGATGAGATTTA
CTCTGACTTTTACGATGACCTTCCTGAGGAGGAGCAATTAATCGTGGAGTGCATGCGCTCAAAAGCAGATGTCTTTTTAA
CTGATAATAGTAATTTAGCCACAAAGTTGTTAGAAGACTATTTTTATCAAACAAAATCAAAATCGCATTATTCGATTAAT
GATTTAATCATAATTGATTTATATATGGTTTGTGCAAATGCTTCAAATTATGAATATTTTATGTTTGATAAAGATGAATT
TATTGGTATAGCTAAGAATCTATTAGAACAAGAAAATCACTTTTCGCTAGCAGAAATTTTTGTCTTAAATAATATTTTAT
TTGGTAGTTTGAGCTTGTTGGTTGATTTAAAAATGTGGGACGAAGTGGAATTGACTTTAGATGTTTTAAAAGGAATTATG
GCTAAAATTCAAGATTTTCATAAGAAGCCAGTTTTGAATATGATTGAGTGGAAGTATATTTTGGAACGTTTTGGTCAAAC
AGAAAAGGCTCAAAAATTATATGAAGAGGCAGTGTTATATGCAAATTTGATAGGTGATGCTTATTTAGCTAATAAAATAA
CAGAAGAATGGATAAAAGATACAACAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (74-297)

• Helix-turn-helix (HTH_3) (10-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.632	94.059	0.495
comR	Streptococcus pyogenes MGAS8232	46.844	99.34	0.465
comR	Streptococcus mutans UA159	46.823	98.68	0.462
comR	Streptococcus pyogenes MGAS315	46.309	98.35	0.455
comR	Streptococcus suis P1/7	39.731	98.02	0.389
comR	Streptococcus suis 05ZYH33	39.731	98.02	0.389
comR	Streptococcus suis D9	37.419	100	0.383