Detailed information NTG1119892

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: EL076_RS05415
• Genome accession: NZ_LR134275
• Coordinates: 1061447..1062154 (-)
• Length: 235 a.a.
• NCBI ID: WP_003093060.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1056447..1067154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS05390 (NCTC12167_01072)	yidA	1056796..1057605 (+)	810	WP_003092782.1	sugar-phosphatase	-
EL076_RS05395 (NCTC12167_01073)	-	1057607..1058821 (+)	1215	WP_064519711.1	aminoacyltransferase	-
EL076_RS05400 (NCTC12167_01074)	-	1058876..1059235 (-)	360	WP_003093009.1	YbaN family protein	-
EL076_RS05405 (NCTC12167_01075)	vicX	1059296..1060108 (-)	813	WP_003093062.1	MBL fold metallo-hydrolase	Regulator
EL076_RS05410 (NCTC12167_01076)	vicK	1060114..1061454 (-)	1341	WP_003092744.1	cell wall metabolism sensor histidine kinase VicK	Regulator
EL076_RS05415 (NCTC12167_01077)	vicR	1061447..1062154 (-)	708	WP_003093060.1	response regulator YycF	Regulator
EL076_RS05420 (NCTC12167_01078)	-	1062441..1063208 (+)	768	WP_126429557.1	amino acid ABC transporter ATP-binding protein	-
EL076_RS05425 (NCTC12167_01079)	-	1063218..1064051 (+)	834	WP_126429559.1	transporter substrate-binding domain-containing protein	-
EL076_RS05430 (NCTC12167_01080)	-	1064069..1064767 (+)	699	WP_126429561.1	amino acid ABC transporter permease	-
EL076_RS05435 (NCTC12167_01081)	-	1064779..1065429 (+)	651	WP_126429563.1	amino acid ABC transporter permease	-
EL076_RS05440 (NCTC12167_01082)	-	1065615..1066382 (+)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27073.95 Da
• Isoelectric Point: 4.8387

>NTDB_id=1119892 EL076_RS05415 WP_003093060.1 1061447..1062154(-) (vicR) [Streptococcus vestibularis strain NCTC12167]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1119892 EL076_RS05415 WP_003093060.1 1061447..1062154(-) (vicR) [Streptococcus vestibularis strain NCTC12167]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATATCGGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGTCGAGAAGCTTTAGAACAATTTGAAGCTGAAAAACCAGACTTGGTTATCCTGGACTTGA
TGTTGCCTGAACTGGATGGCTTGGAAGTAGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATTATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACTATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTGCTCTTCCATTTGGCAACACATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGTTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACTATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.957	100	0.86
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.455	98.298	0.447
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
scnR	Streptococcus mutans UA159	38.559	100	0.387