Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   EL076_RS05410 Genome accession   NZ_LR134275
Coordinates   1060114..1061454 (-) Length   446 a.a.
NCBI ID   WP_003092744.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1055114..1066454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS05380 (NCTC12167_01070) - 1055293..1055679 (-) 387 WP_126429553.1 DUF1934 domain-containing protein -
  EL076_RS05385 (NCTC12167_01071) - 1055754..1056617 (-) 864 WP_126429555.1 GNAT family N-acetyltransferase -
  EL076_RS05390 (NCTC12167_01072) yidA 1056796..1057605 (+) 810 WP_003092782.1 sugar-phosphatase -
  EL076_RS05395 (NCTC12167_01073) - 1057607..1058821 (+) 1215 WP_064519711.1 aminoacyltransferase -
  EL076_RS05400 (NCTC12167_01074) - 1058876..1059235 (-) 360 WP_003093009.1 YbaN family protein -
  EL076_RS05405 (NCTC12167_01075) vicX 1059296..1060108 (-) 813 WP_003093062.1 MBL fold metallo-hydrolase Regulator
  EL076_RS05410 (NCTC12167_01076) vicK 1060114..1061454 (-) 1341 WP_003092744.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL076_RS05415 (NCTC12167_01077) vicR 1061447..1062154 (-) 708 WP_003093060.1 response regulator YycF Regulator
  EL076_RS05420 (NCTC12167_01078) - 1062441..1063208 (+) 768 WP_126429557.1 amino acid ABC transporter ATP-binding protein -
  EL076_RS05425 (NCTC12167_01079) - 1063218..1064051 (+) 834 WP_126429559.1 transporter substrate-binding domain-containing protein -
  EL076_RS05430 (NCTC12167_01080) - 1064069..1064767 (+) 699 WP_126429561.1 amino acid ABC transporter permease -
  EL076_RS05435 (NCTC12167_01081) - 1064779..1065429 (+) 651 WP_126429563.1 amino acid ABC transporter permease -
  EL076_RS05440 (NCTC12167_01082) - 1065615..1066382 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50966.28 Da        Isoelectric Point: 6.0386

>NTDB_id=1119891 EL076_RS05410 WP_003092744.1 1060114..1061454(-) (vicK) [Streptococcus vestibularis strain NCTC12167]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRQAKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELADRLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDRESATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALHE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNPGKFYEIIRDYSVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1119891 EL076_RS05410 WP_003092744.1 1060114..1061454(-) (vicK) [Streptococcus vestibularis strain NCTC12167]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTATTTGTTGCTTTCTATTTTAT
TTTTTTAGCTTATCGTGATTATCGACAAGCTAAAAATATCCGAAAGTTGACTAAGAGAGTCAAGTCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCGGATCGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCGTGGTCAGATTACCATGATTAATAGCACTGCTCAACGCTTGTTGAATTTAGATCGCGAAAGTGCGA
CTCAGATGTCTATTTTGGATTTATTAGATGGTGAGAATCCCTACACCTATAGTGAATTGTTGTCTAAGACGCCCGAAATC
CATCTGTCGCGTCGAGATGCTAATGATGAATTTGTGACGCTACGTGTTAATTTTGCACTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAACAGGAAAAAGAGGAGCGTGAACGTCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACACCTTTGACTTCAGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCCACGAA
GAAATTGCTCCAAACTTTATTAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
GTCTCGAATTGACAATAAAAGCACACAGCTTGATGTCGAAATGACAAACTTTACAGCCTTTATGACCTATATATTGAATC
GGTTTGATCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTTTTATGAAATCATTAGAGATTACTCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACTCAGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACGACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAGGATTTGCCGTTGATTTTCGACCGTTTTTACCGCGTTGATAAGGCCAGAAGTCGTGCTCAAGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

92.825

0.688
  micB Streptococcus pneumoniae Cp1015

67.436

97.085

0.655

Multiple sequence alignment