Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EL086_RS01685 Genome accession   NZ_LR134274
Coordinates   319683..320582 (+) Length   299 a.a.
NCBI ID   WP_038675281.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC8618     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 314683..325582
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS01665 (NCTC8618_02743) trkA 315852..317201 (-) 1350 WP_022496357.1 Trk system potassium transporter TrkA -
  EL086_RS01670 (NCTC8618_02745) - 317493..318002 (+) 510 WP_002883735.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  EL086_RS01675 (NCTC8618_02747) - 318292..318849 (+) 558 WP_022496034.1 ECF transporter S component -
  EL086_RS01680 (NCTC8618_02748) - 318852..319502 (+) 651 WP_038675279.1 phosphatase PAP2 family protein -
  EL086_RS01685 (NCTC8618_02749) comR 319683..320582 (+) 900 WP_038675281.1 helix-turn-helix transcriptional regulator Regulator
  EL086_RS01690 (NCTC8618_02750) comA 320757..322853 (+) 2097 WP_038675283.1 peptide cleavage/export ABC transporter Regulator
  EL086_RS01695 (NCTC8618_02751) - 322978..323310 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  EL086_RS01700 (NCTC8618_02752) - 323362..324753 (-) 1392 WP_038675284.1 DUF4153 domain-containing protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35169.68 Da        Isoelectric Point: 5.8538

>NTDB_id=1119801 EL086_RS01685 WP_038675281.1 319683..320582(+) (comR) [Streptococcus salivarius strain NCTC8618]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDKLSYIAKRLGKNMSDLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKSKLALIEEVYEKFFELLPEEELLTLDILENILSFTNWEESPKVEEIYEDLFEQVKRKKKFST
NDLLVIDYYFFHLYGRKQFDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKKAAENYDKAIMFASVLEDSVLEESIKAGKAADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=1119801 EL086_RS01685 WP_038675281.1 319683..320582(+) (comR) [Streptococcus salivarius strain NCTC8618]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGTCAGCAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTGCGTCAGTTAATTCGTATTGAAAAAGGGGAGTCACTCCCGTCTTTGGATAAATTATCTT
ATATTGCAAAACGTCTAGGAAAAAATATGTCTGATCTATTGGATCATGACAATATTACCATTCCTGACGAATATTATGAG
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAATCCAGAAAGAATAAAGTCTAAACTTGCCTTAATTGAGGAAGT
CTATGAGAAATTCTTTGAACTTCTTCCAGAAGAAGAGTTGTTAACTCTAGATATTTTGGAAAATATTTTGAGTTTTACTA
ATTGGGAGGAGAGCCCAAAGGTTGAAGAAATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAAGAAATTCTCAACT
AACGATTTATTAGTTATTGACTATTATTTCTTCCATCTCTATGGAAGAAAACAGTTTGACAAAAAACTTTTTGAAAGGAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGACGATGTCTATAATATTGTTTTATTTAATGATTTGATGGCTATCG
CTGCTTTGAAGATTTTTCACAATTCCTTTTCAGACTTCTTAACAGTTGTGGATAAAGCATTAGCCGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCTAAATATGAACTTCTGCATAAGGGAAATAAGAAAAAGGC
TGCAGAGAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTTTTAGAAGAAAGTATAAAAGCAGGGA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

97.659

100

0.977
  comR Streptococcus salivarius SK126

96.99

100

0.97
  comR Streptococcus thermophilus LMG 18311

94.314

100

0.943
  comR Streptococcus thermophilus LMD-9

93.645

100

0.936
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.809

100

0.428
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.475

100

0.425

Multiple sequence alignment